Free Flap Reconstruction
Conditions
Brief summary
Free flap reconstruction consists in replacing tissular defect from one body part by another tissu harvested in a distant site. Microsurgery has to be performed to restore vascularization. Free flaps are now the gold standard in complex reconstruction. While reliable with a success rate superior to 95 %, a failure takes a heavy burden on the patient. Many risk factors have been highlitghted in free flap failure for head and neck microvascular reconstruction. Among them, malnutrition is still debated. This is a retrospective cohort study comparing complications occurrence between two groups. One group with normal nutritionnal status, the other with malnutrition. Between january 2008 and january 2018, 70 patients who underwent oral cavity reconstruction using free flap were included. This is the first study known to date which uses clinical and biological variables to determine the nutritionnal status. Malnutrition is not associated with a higher risk for free flap failure in the oral cavity.
Interventions
PROCEDUREFree flap
Free flap reconstruction of the oral cavity
Sponsors
Centre Hospitalier Universitaire Dijon
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* every consenting patients undergoing free flap reconstruction of the oral cavity
Exclusion criteria
* unable to give consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Major complication occurency | 1 month | in the first-month post-operative period, complications leading to flap loss |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Minor complication occurency | 1 month | in the first-month post-operative period, complications NOT leading to flap loss |
Countries
France
Outcome results
None listed