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Donor Gender Effect on Graft Function in Adult Egyptian Patients Undergoing Living Donor Liver Transplant

Donor Gender Effect on Graft Function in Adult Egyptian Patients Undergoing Living Donor Liver Transplant: A Single Centre Retrospective Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04068363
Enrollment
342
Registered
2019-08-28
Start date
2019-08-15
Completion date
2021-06-20
Last updated
2022-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Donor to Recipient Gender Mismatch in LDLT

Brief summary

Liver transplantation (LT) represents the gold-standard therapy for the treatment in case of dreadful liver pathologies . It is thus a main concern to optimize the results in terms of post-LT survivals. The effect of gender match on post-transplant outcome is still debatable. Hormonal , and size difference between female and male may be proposed to affect the post transplant outcome . The aim of this study is to evaluate the effect of donor-recipient gender mismatch on survival rates

Interventions

OTHERnon interventional

non interventional study

Sponsors

Ain Shams University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adult Egyptian Patients \>18 years.

Exclusion criteria

* Patient refusal. * Patients who underwent re-transplantation before discharge from the ICU after the first liver transplant. * Intraoperative cardiac arrest or immediately postoperative cardiac arrest within the first 6 hours postoperative. * Massive blood loss. * Pre-existing renal failure requiring hemodialysis or continuous hemofiltration. * Pregnancy.

Design outcomes

Primary

MeasureTime frameDescription
2 years survival post liver transplant.3 monthsThe primary outcome will be survival at 2 years post liver transplant

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026