Amblyopia, Anisometropia
Conditions
Brief summary
Adaptica (Padova, Italy) designed a fixed-distance, dark portable tube with power and remote control for the 2WIN: photoscreener. GoChecksKids designed a flash-concentrating case for the iPhone 7+ to more quickly achieve two-axis photoscreen. These devices were compared to confirmatory exams in children and young adults in a remote Burma clinic and in an Alaskan pediatric ophthalmology practice.
Detailed description
Photoscreening with follow up confirmatory exams for referred and passed interpretations were offered to children and young adults at a remote clinic in the Karen State of eastern Burma (Myanmar). The clinic had intermittent 220 Volt power generator, but no internet or cell phone coverage. Consecutive patients in a WiFi-equipped pediatric ophthalmology practice in Anchorage, Alaska had photoscreening before confirmatory examination. Each patient had photoscreening with the 2WIN photoscreener installed in the Kaleidos housing. In Anchorage, the devise was controled by the wireless tablet computer. In Burma, however, despite a WiFi router not connected to internet, the tablet computer would not connect to the 2WIN and therefore the Kaleidos read-trap door was opened so the 2WIN could be activated and controlled manually. The 2WIN stored results on an micro-SD memory card which was eventually downloaded to computer. Each patient also had photoscreening with GoCheckKids (GCK) on an iPhone 7 Plus using the enhanced, flash-concentrating cell-phone case. In Anchorage, in addition to on-site smart-phone interpretation, images were uploaded to the central reading center for secondary interpretation. In Burma, all images were retained on the smart phone and eventually uploaded for GoCheckKids central secondary analysis after return to urban internet availability. In Burma, a portable, light-wieght tent was used to provide a dim screening environment with less distraction. Confirmatory exams were performed consistent with 2003 and 2013 American Association for Pediatric Ophthalmology and Strabismus (AAPOS) uniform guidelines. Cycloplegic refractions were performed 20-40 minutes after cyclopentolate 1% instillation. Visual acuity was checked with patched, surround HOTV at 3 meters threshold with at least 3 of 4 optotypes correct. Validation was performed with conventional 2 x 2 screen-exam matrix, and also with Alaska Blind Child Discovery (ABCD) 3 x 3 matrix including inconclusive results (no instrument interpretation or unable to gain a reading) with inconclusive interpretations considered a referral.
Interventions
Determine amblyopia risk factors
Sponsors
Study design
Eligibility
Inclusion criteria
* at least one eye
Exclusion criteria
* bilateral enucleation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Amblyopia Rick Factor prevalence | February 15, 2019 through April 16, 2019 | AAPOS 2003 and 2013 defined ARFs |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Refractive Error | February 15, 2019 through April 16, 2019 | Glasses prescription |
Countries
United States