Liver Diseases, Physical Stress, Postoperative Complications, Surgery
Conditions
Keywords
laparoscopic, minimal invasive, physical recovery, liver surgery
Brief summary
The role of laparoscopic liver surgery with respect to clinical outcome remains unclear.
Detailed description
The role of laparoscopic liver surgery with respect to clinical outcome remains unclear. The investigators hypothesized that laparoscopic liver resection (LLR) is associated with better postoperative recovery than open liver resection (OLR). Twenty-one patients who underwent LR were included in this study (11 OLR (52.4%) and 10 LLR (47.6%), respectively). Postoperative recovery was measured by bicycle stress testing at months 1 and 6 after surgery and compared to preoperative stress testing. Standardized performance for bicycle stress testing was calculated based on age, sex, height and weight. Postoperative recovery was compared between groups as change of performance (%).
Interventions
OTHERErgometry
Patients underwent a preoperative ergometry to assess their physical fitness prior to their planned liver resection. Bicycle stress testing was performed preoperatively and 1 and 6 months postoperatively.
Sponsors
Medical University of Vienna
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Intervention model description
non-randomized cohort study, 2 parallel groups
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* all patients undergoing liver resection (open vs. laparoscopic) * all patients willing participate and gave written informed consent
Exclusion criteria
* pregnancy * significant traumatic injury within 30 days prior to study enrolment * inability or unwillingness to comply to the protocol or to perform bicycle ergometry
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Overall change in performance | 1, 6 months | The change in performance after 1 and 6 months postoperatively in comparison to preoperative ergometry. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative Complications | 1 months | Secondary endpoints included postoperative complications (wound healing, liver failure, adverse events) |
| Liver resection and effect on postoperative fitness | 2 years | patients were divided into two groups ( major (\>2 segments) vs. minor (≤2segments) liver resection) and postoperative performance was evaluated |
| length of stay | 1 month | Length of postoperative hospital stay |
Countries
Austria
Outcome results
None listed