Ametropia
Conditions
Brief summary
The aim of this work is to investigate the clinical performance and subjective acceptance of the comfilcon A asphere contact lens when compared to single-vision spectacles in subjects who have never worn contact lenses and who use digital devices (such as phones, tablets, laptops, desktop computers) for at least 4 hours per day on at least 5 days per week.
Detailed description
The aim of this clinical work is to compare the clinical performance and subjective acceptance of comfilcon A asphere contact lens when compared to single-vision spectacles in subjects who use digital devices (phones, tablets, laptops, desktop computers) for at least 4 hours per day on at least 5 days per week. Subjects will be randomized to use either their habitual spectacles or the study contact lenses for two months.
Interventions
DEVICEcomfilcon A asphere
Contact Lens
DEVICESpectacles
Habitual spectacles
Sponsors
CooperVision, Inc.
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* They are between 18 and 35 years of age (inclusive). * They understand their rights as a research subject and are willing and able to sign a Statement of Informed Consent. * They are willing and able to follow the protocol. * They are a 'neophyte' (i.e. someone who has not worn contact lenses previously, with the exception for the purposes of a trial fitting, lasting up to one week). * They have a contact lens spherical prescription between -1.00 to -6.25D (inclusive) based on the ocular refraction. * They have a cylindrical correction of -0.875DC or less in each eye based on the ocular refraction * They own and habitually wear single vision spectacles used for both distance and near vision, including computer and digital device use. * Their single vision spectacles have a mean sphere equivalent within ±0.50D of that of the refraction found in the study for each eye (after having taken lens effectivity into account). * They are willing to be fitted with contact lenses and understand they may be randomized to either group. * They are willing to wear the contact lenses (if relevant) or spectacles for at least 8 hours per day, 5 days per week. * They typically use digital devices for a minimum of 4 hours per day, 5 days per week. * They agree not to change the spectacles they will wear for digital device use for the duration of the study. * They agree not to participate in other clinical research for the duration of the study.
Exclusion criteria
* They have an ocular disorder which would normally contra-indicate contact lens wear. * They have a systemic disorder which would normally contra-indicate contact lens wear. * They are using any topical medication such as eye drops (including comfort drops) or ointment on a regular basis. * The spectacles they use for digital device viewing on the study have been made with specialist features for computer use, digital eye fatigue or are multifocal/bifocal. * They are aphakic. * They have had corneal refractive surgery. * They have any corneal distortion resulting from previous hard or rigid lens wear or have keratoconus. * They are pregnant or breastfeeding. * They have any infectious disease which would, in the opinion of the investigator, contraindicate contact lens wear or pose a risk to study personnel; or they have any immunosuppressive disease (e.g. HIV), or a history of anaphylaxis or severe allergic reaction. * They have evidence of a heterotropia or decompensating heterotropia on cover test. * They have a history of having been prescribed prism in their spectacles (by self report). * They have taken part in any other contact lens or care solution clinical trial or research, within two weeks prior to starting this study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Symptom of Difficulty Focusing For Near Vision | Baseline | Symptom of difficulty focusing for near vision measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense). |
| Symptom of Burning | Baseline | Symptom of burning measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense). |
| Symptom of Itching | Baseline | Symptom of itching measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense). |
| Symptom of Feeling of Foreign Body | Baseline | Symptom of feeling of foreign body measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense). |
| Symptom of Tearing | Baseline | Symptom of tearing measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense). |
| Symptom of Excessive Blinking | Baseline | Symptom of excessive blinking measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense). |
| Symptom of Increased Sensitivity to Light | Baseline | Symptom of increased sensitivity to light measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense). |
| Symptom of Eye Redness | Baseline | Symptom of eye redness measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense). |
| Symptom of Eye Pain | Baseline | Symptom of eye pain measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense). |
| Symptom of Heavy Eyelids | Baseline | Symptom of heavy eyelids measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense). |
| Symptom of Dryness | Baseline | Symptom of dryness measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense). |
| Symptom of Blurred Vision | Baseline | Symptom of blurred vision measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense). |
| Symptom of Double Vision | Baseline | Symptom of double vision measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense). |
| Symptom of Colored Haloes Around Objects | Baseline | Symptom of colored haloes around objects measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense). |
| Symptom of Colored Halos Around Objects | Two Months | Symptom of colored halos around objects measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense). |
| Symptom of Feeling That Sight is Worsening | Baseline | Symptom of feeling that sight is worsening measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense). |
| Symptom of Headache | Baseline | Symptom of headache measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense). |
Countries
United Kingdom
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| Comfilcon A Asphere Subjects were randomized to use the study contact lenses for two months. | 32 |
| Habitual Spectacles Subjects were randomized to wear habitual spectacles for two months. | 29 |
| Total | 61 |
Withdrawals & dropouts
| Period | Reason | FG000 | FG001 |
|---|---|---|---|
| One Month | Lost to Follow-up | 4 | 0 |
| Two Month | Adverse Event | 1 | 0 |
| Two Month | Lost to Follow-up | 1 | 0 |
Baseline characteristics
| Characteristic | Habitual Spectacles | Total | Comfilcon A Asphere |
|---|---|---|---|
| Age, Categorical <=18 years | 0 Participants | 0 Participants | 0 Participants |
| Age, Categorical >=65 years | 0 Participants | 0 Participants | 0 Participants |
| Age, Categorical Between 18 and 65 years | 29 Participants | 61 Participants | 32 Participants |
| Age, Continuous | 22.9 years STANDARD_DEVIATION 4.4 | 23.7 years STANDARD_DEVIATION 4.2 | 24.4 years STANDARD_DEVIATION 3.9 |
| Race and Ethnicity Not Collected | — | 0 Participants | — |
| Region of Enrollment United Kingdom | 29 participants | 61 participants | 32 participants |
| Sex: Female, Male Female | 18 Participants | 38 Participants | 20 Participants |
| Sex: Female, Male Male | 11 Participants | 23 Participants | 12 Participants |
Adverse events
| Event type | EG000 affected / at risk | EG001 affected / at risk |
|---|---|---|
| deaths Total, all-cause mortality | 0 / 32 | 0 / 29 |
| other Total, other adverse events | 1 / 32 | 0 / 29 |
| serious Total, serious adverse events | 0 / 32 | 0 / 29 |
Outcome results
Primary
Symptom of Blurred Vision
Symptom of blurred vision measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Baseline
Population: Intensity of symptom of blurred vision was measured only for subjects who had frequency of symptom of blurred vision on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Blurred Vision | Frequency | 0.34 units on a scale | Standard Deviation 0.48 |
| Comfilcon A Asphere | Symptom of Blurred Vision | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Blurred Vision | Frequency | 0.45 units on a scale | Standard Deviation 0.51 |
| Habitual Spectacles | Symptom of Blurred Vision | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Blurred Vision
Symptom of blurred vision measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: One Month
Population: One subject score was not measured for Habitual spectacles group. Intensity of symptom of blurred vision was measured only for subjects who had frequency of symptom of blurred vision on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Blurred Vision | Frequency | 0.54 units on a scale | Standard Deviation 0.58 |
| Comfilcon A Asphere | Symptom of Blurred Vision | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Blurred Vision | Frequency | 0.25 units on a scale | Standard Deviation 0.44 |
| Habitual Spectacles | Symptom of Blurred Vision | Intensity | 1.14 units on a scale | Standard Deviation 0.38 |
Primary
Symptom of Blurred Vision
Symptom of blurred vision measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Two Months
Population: Intensity of symptom of blurred vision was measured only for subjects who had frequency of symptom of blurred vision on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Blurred Vision | Frequency | 0.35 units on a scale | Standard Deviation 0.49 |
| Comfilcon A Asphere | Symptom of Blurred Vision | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Blurred Vision | Frequency | 0.28 units on a scale | Standard Deviation 0.45 |
| Habitual Spectacles | Symptom of Blurred Vision | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Burning
Symptom of burning measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Baseline
Population: Intensity of symptom of burning was measured only for subjects who had frequency of symptom of burning on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Burning | Frequency | 0.16 units on a scale | Standard Deviation 0.37 |
| Comfilcon A Asphere | Symptom of Burning | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Burning | Frequency | 0.21 units on a scale | Standard Deviation 0.49 |
| Habitual Spectacles | Symptom of Burning | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Burning
Symptom of burning measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: 1 month
Population: One subject scores was not measured for Habitual spectacles group. Intensity of symptom of burning was measured only for subjects who had frequency of symptom of burning on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Burning | Frequency | 0.11 units on a scale | Standard Deviation 0.31 |
| Comfilcon A Asphere | Symptom of Burning | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Burning | Frequency | 0.29 units on a scale | Standard Deviation 0.53 |
| Habitual Spectacles | Symptom of Burning | Intensity | 1.14 units on a scale | Standard Deviation 0.38 |
Primary
Symptom of Burning
Symptom of burning measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: 2 months
Population: Intensity of symptom of burning was measured only for subjects who had frequency of symptom of burning on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Burning | Frequency | 0.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Burning | Frequency | 0.17 units on a scale | Standard Deviation 0.38 |
| Habitual Spectacles | Symptom of Burning | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Colored Haloes Around Objects
Symptom of colored haloes around objects measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: One Month
Population: One subject score was not measured for Habitual spectacles group. Intensity of symptom of colored haloes around objects was measured only for subjects who had frequency of symptom of colored haloes around objects on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Colored Haloes Around Objects | Frequency | 0.11 units on a scale | Standard Deviation 0.31 |
| Comfilcon A Asphere | Symptom of Colored Haloes Around Objects | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Colored Haloes Around Objects | Frequency | 0.07 units on a scale | Standard Deviation 0.26 |
| Habitual Spectacles | Symptom of Colored Haloes Around Objects | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Colored Haloes Around Objects
Symptom of colored haloes around objects measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Baseline
Population: Intensity of symptom of colored haloes around objects was measured only for subjects who had frequency of symptom of colored haloes around objects on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Colored Haloes Around Objects | Frequency | 0.16 units on a scale | Standard Deviation 0.45 |
| Comfilcon A Asphere | Symptom of Colored Haloes Around Objects | Intensity | 1.25 units on a scale | Standard Deviation 0.5 |
| Habitual Spectacles | Symptom of Colored Haloes Around Objects | Frequency | 0.17 units on a scale | Standard Deviation 0.47 |
| Habitual Spectacles | Symptom of Colored Haloes Around Objects | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Colored Halos Around Objects
Symptom of colored halos around objects measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Two Months
Population: Intensity of symptom of colored haloes around objects was measured only for subjects who had frequency of symptom of colored haloes around objects on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Colored Halos Around Objects | Frequency | 0.10 units on a scale | Standard Deviation 0.31 |
| Comfilcon A Asphere | Symptom of Colored Halos Around Objects | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Colored Halos Around Objects | Frequency | 0.07 units on a scale | Standard Deviation 0.26 |
| Habitual Spectacles | Symptom of Colored Halos Around Objects | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Difficulty Focusing For Near Vision
Symptom of difficulty focusing for near vision measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Two Months
Population: Intensity of symptom of difficulty focusing for near vision was measured only for subjects who had frequency of symptom of difficulty focusing for near vision on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Difficulty Focusing For Near Vision | Frequency | 0.45 units on a scale | Standard Deviation 0.51 |
| Comfilcon A Asphere | Symptom of Difficulty Focusing For Near Vision | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Difficulty Focusing For Near Vision | Frequency | 0.14 units on a scale | Standard Deviation 0.35 |
| Habitual Spectacles | Symptom of Difficulty Focusing For Near Vision | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Difficulty Focusing For Near Vision
Symptom of difficulty focusing for near vision measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: One Month
Population: One subject score was not measured for Habitual spectacles group. Intensity of symptom of difficulty focusing for near vision was measured only for subjects who had frequency of symptom of difficulty focusing for near vision on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Difficulty Focusing For Near Vision | Frequency | 0.18 units on a scale | Standard Deviation 0.39 |
| Comfilcon A Asphere | Symptom of Difficulty Focusing For Near Vision | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Difficulty Focusing For Near Vision | Frequency | 0.29 units on a scale | Standard Deviation 0.46 |
| Habitual Spectacles | Symptom of Difficulty Focusing For Near Vision | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Difficulty Focusing For Near Vision
Symptom of difficulty focusing for near vision measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Baseline
Population: Intensity of symptom of difficulty focusing for near vision was measured only for subjects who had frequency of symptom of difficulty focusing for near vision on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Difficulty Focusing For Near Vision | Frequency | 0.28 units on a scale | Standard Deviation 0.46 |
| Comfilcon A Asphere | Symptom of Difficulty Focusing For Near Vision | Intensity | 1.10 units on a scale | Standard Deviation 0.32 |
| Habitual Spectacles | Symptom of Difficulty Focusing For Near Vision | Frequency | 0.41 units on a scale | Standard Deviation 0.57 |
| Habitual Spectacles | Symptom of Difficulty Focusing For Near Vision | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Double Vision
Symptom of double vision measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Baseline
Population: Intensity of symptom of double vision was measured only for subjects who had frequency of symptom of double vision on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Double Vision | Frequency | 0.06 units on a scale | Standard Deviation 0.25 |
| Comfilcon A Asphere | Symptom of Double Vision | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Double Vision | Frequency | 0.07 units on a scale | Standard Deviation 0.37 |
| Habitual Spectacles | Symptom of Double Vision | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Double Vision
Symptom of double vision measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: One Month
Population: One subject score was not measured for Habitual spectacles group. Intensity of symptom of double vision was measured only for subjects who had frequency of symptom of double vision on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Double Vision | Frequency | 0.11 units on a scale | Standard Deviation 0.31 |
| Comfilcon A Asphere | Symptom of Double Vision | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Double Vision | Frequency | 0.07 units on a scale | Standard Deviation 0.26 |
| Habitual Spectacles | Symptom of Double Vision | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Double Vision
Symptom of double vision measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Two Months
Population: Intensity of symptom of double vision was measured only for subjects who had frequency of symptom of double vision on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Double Vision | Frequency | 0.05 units on a scale | Standard Deviation 0.22 |
| Comfilcon A Asphere | Symptom of Double Vision | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Double Vision | Frequency | 0.07 units on a scale | Standard Deviation 0.26 |
| Habitual Spectacles | Symptom of Double Vision | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Dryness
Symptom of dryness measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Baseline
Population: Intensity of symptom of dryness was measured only for subjects who had frequency of symptom of dryness on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Dryness | Frequency | 0.38 units on a scale | Standard Deviation 0.55 |
| Comfilcon A Asphere | Symptom of Dryness | Intensity | 1.18 units on a scale | Standard Deviation 0.4 |
| Habitual Spectacles | Symptom of Dryness | Frequency | 0.48 units on a scale | Standard Deviation 0.51 |
| Habitual Spectacles | Symptom of Dryness | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Dryness
Symptom of dryness measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: One Month
Population: One subject score was not measured for Habitual spectacles group. Intensity of symptom of dryness was measured only for subjects who had frequency of symptom of dryness on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Dryness | Frequency | 0.75 units on a scale | Standard Deviation 0.7 |
| Comfilcon A Asphere | Symptom of Dryness | Intensity | 1.06 units on a scale | Standard Deviation 0.24 |
| Habitual Spectacles | Symptom of Dryness | Frequency | 0.43 units on a scale | Standard Deviation 0.5 |
| Habitual Spectacles | Symptom of Dryness | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Dryness
Symptom of dryness measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Two Months
Population: Intensity of symptom of dryness was measured only for subjects who had frequency of symptom of dryness on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Dryness | Frequency | 0.75 units on a scale | Standard Deviation 0.55 |
| Comfilcon A Asphere | Symptom of Dryness | Intensity | 1.07 units on a scale | Standard Deviation 0.27 |
| Habitual Spectacles | Symptom of Dryness | Frequency | 0.48 units on a scale | Standard Deviation 0.57 |
| Habitual Spectacles | Symptom of Dryness | Intensity | 1.15 units on a scale | Standard Deviation 0.38 |
Primary
Symptom of Excessive Blinking
Symptom of excessive blinking measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Two Months
Population: Intensity of symptom of excessive blinking was measured only for subjects who had frequency of symptom of excessive blinking on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Excessive Blinking | Frequency | 0.35 units on a scale | Standard Deviation 0.49 |
| Comfilcon A Asphere | Symptom of Excessive Blinking | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Excessive Blinking | Frequency | 0.17 units on a scale | Standard Deviation 0.38 |
| Habitual Spectacles | Symptom of Excessive Blinking | Intensity | 1.20 units on a scale | Standard Deviation 0.45 |
Primary
Symptom of Excessive Blinking
Symptom of excessive blinking measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: One Month
Population: One subject score was not measured for Habitual spectacles group. Intensity of symptom of excessive blinking was measured only for subjects who had frequency of symptom of excessive blinking on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Excessive Blinking | Frequency | 0.46 units on a scale | Standard Deviation 0.51 |
| Comfilcon A Asphere | Symptom of Excessive Blinking | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Excessive Blinking | Frequency | 0.29 units on a scale | Standard Deviation 0.53 |
| Habitual Spectacles | Symptom of Excessive Blinking | Intensity | 1.14 units on a scale | Standard Deviation 0.38 |
Primary
Symptom of Excessive Blinking
Symptom of excessive blinking measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Baseline
Population: Intensity of symptom of excessive blinking was measured only for subjects who had frequency of symptom of excessive blinking on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Excessive Blinking | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Comfilcon A Asphere | Symptom of Excessive Blinking | Frequency | 0.25 units on a scale | Standard Deviation 0.51 |
| Habitual Spectacles | Symptom of Excessive Blinking | Intensity | 1.10 units on a scale | Standard Deviation 0.32 |
| Habitual Spectacles | Symptom of Excessive Blinking | Frequency | 0.38 units on a scale | Standard Deviation 0.56 |
Primary
Symptom of Eye Pain
Symptom of eye pain measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: One Month
Population: One subject score was not measured for Habitual spectacles group. Intensity of symptom of eye pain was measured only for subjects who had frequency of symptom of eye pain on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Eye Pain | Frequency | 0.14 units on a scale | Standard Deviation 0.36 |
| Comfilcon A Asphere | Symptom of Eye Pain | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Eye Pain | Frequency | 0.25 units on a scale | Standard Deviation 0.44 |
| Habitual Spectacles | Symptom of Eye Pain | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Eye Pain
Symptom of eye pain measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Two Months
Population: Intensity of symptom of eye pain was measured only for subjects who had frequency of symptom of eye pain on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Eye Pain | Frequency | 0.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Eye Pain | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Eye Pain | Frequency | 0.31 units on a scale | Standard Deviation 0.54 |
Primary
Symptom of Eye Pain
Symptom of eye pain measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Baseline
Population: Intensity of symptom of eye pain was measured only for subjects who had frequency of symptom of eye pain on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Eye Pain | Frequency | 0.34 units on a scale | Standard Deviation 0.55 |
| Comfilcon A Asphere | Symptom of Eye Pain | Intensity | 1.10 units on a scale | Standard Deviation 0.32 |
| Habitual Spectacles | Symptom of Eye Pain | Frequency | 0.34 units on a scale | Standard Deviation 0.61 |
| Habitual Spectacles | Symptom of Eye Pain | Intensity | 1.13 units on a scale | Standard Deviation 0.35 |
Primary
Symptom of Eye Redness
Symptom of eye redness measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Two Months
Population: Intensity of symptom of eye redness was measured only for subjects who had frequency of symptom of eye redness on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Eye Redness | Frequency | 0.20 units on a scale | Standard Deviation 0.41 |
| Comfilcon A Asphere | Symptom of Eye Redness | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Eye Redness | Frequency | 0.24 units on a scale | Standard Deviation 0.44 |
| Habitual Spectacles | Symptom of Eye Redness | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Eye Redness
Symptom of eye redness measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Baseline
Population: Intensity of symptom of eye redness was measured only for subjects who had frequency of symptom of eye redness on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Eye Redness | Frequency | 0.28 units on a scale | Standard Deviation 0.46 |
| Comfilcon A Asphere | Symptom of Eye Redness | Intensity | 1.11 units on a scale | Standard Deviation 0.33 |
| Habitual Spectacles | Symptom of Eye Redness | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Eye Redness | Frequency | 0.21 units on a scale | Standard Deviation 0.41 |
Primary
Symptom of Eye Redness
Symptom of eye redness measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: One Month
Population: One subject score was not measured for Habitual spectacles group. Intensity of symptom of eye redness was measured only for subjects who had frequency of symptom of eye redness on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Eye Redness | Frequency | 0.36 units on a scale | Standard Deviation 0.56 |
| Comfilcon A Asphere | Symptom of Eye Redness | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Eye Redness | Frequency | 0.18 units on a scale | Standard Deviation 0.39 |
| Habitual Spectacles | Symptom of Eye Redness | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Feeling of Foreign Body
Symptom of feeling of foreign body measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: One Month
Population: One subject score was not measured for Habitual spectacles group. Intensity of feeling of foreign body was measured only for subjects who had frequency of feeling of foreign body on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Feeling of Foreign Body | Frequency | 0.75 units on a scale | Standard Deviation 0.59 |
| Comfilcon A Asphere | Symptom of Feeling of Foreign Body | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Feeling of Foreign Body | Frequency | 0.11 units on a scale | Standard Deviation 0.31 |
| Habitual Spectacles | Symptom of Feeling of Foreign Body | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Feeling of Foreign Body
Symptom of feeling of foreign body measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Baseline
Population: Intensity of feeling of foreign body was measured only for subjects who had frequency of feeling of foreign body on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Feeling of Foreign Body | Frequency | 0.19 units on a scale | Standard Deviation 0.4 |
| Comfilcon A Asphere | Symptom of Feeling of Foreign Body | Intensity | 1.33 units on a scale | Standard Deviation 0.52 |
| Habitual Spectacles | Symptom of Feeling of Foreign Body | Frequency | 0.17 units on a scale | Standard Deviation 0.38 |
| Habitual Spectacles | Symptom of Feeling of Foreign Body | Intensity | 1.20 units on a scale | Standard Deviation 0.45 |
Primary
Symptom of Feeling of Foreign Body
Symptom of feeling of foreign body measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Two Months
Population: Intensity of feeling of foreign body was measured only for subjects who had frequency of feeling of foreign body on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Feeling of Foreign Body | Frequency | 0.50 units on a scale | Standard Deviation 0.61 |
| Comfilcon A Asphere | Symptom of Feeling of Foreign Body | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Feeling of Foreign Body | Frequency | 0.21 units on a scale | Standard Deviation 0.41 |
| Habitual Spectacles | Symptom of Feeling of Foreign Body | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Feeling That Sight is Worsening
Symptom of feeling that sight is worsening measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Two Months
Population: Intensity of symptom of feeling that sight is worsening was measured only for subjects who had frequency of symptom of feeling that sight is worsening on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Feeling That Sight is Worsening | Frequency | 0.20 units on a scale | Standard Deviation 0.41 |
| Comfilcon A Asphere | Symptom of Feeling That Sight is Worsening | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Feeling That Sight is Worsening | Frequency | 0.45 units on a scale | Standard Deviation 0.63 |
| Habitual Spectacles | Symptom of Feeling That Sight is Worsening | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Feeling That Sight is Worsening
Symptom of feeling that sight is worsening measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: One Month
Population: One subject score was not measured for Habitual spectacles group. Intensity of symptom of feeling that sight is worsening was measured only for subjects who had frequency of symptom of feeling that sight is worsening on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Feeling That Sight is Worsening | Frequency | 0.25 units on a scale | Standard Deviation 0.44 |
| Comfilcon A Asphere | Symptom of Feeling That Sight is Worsening | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Feeling That Sight is Worsening | Frequency | 0.36 units on a scale | Standard Deviation 0.49 |
| Habitual Spectacles | Symptom of Feeling That Sight is Worsening | Intensity | 1.10 units on a scale | Standard Deviation 0.32 |
Primary
Symptom of Feeling That Sight is Worsening
Symptom of feeling that sight is worsening measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Baseline
Population: Intensity of symptom of feeling that sight is worsening was measured only for subjects who had frequency of symptom of feeling that sight is worsening on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Feeling That Sight is Worsening | Frequency | 0.34 units on a scale | Standard Deviation 0.6 |
| Comfilcon A Asphere | Symptom of Feeling That Sight is Worsening | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Feeling That Sight is Worsening | Frequency | 0.48 units on a scale | Standard Deviation 0.51 |
| Habitual Spectacles | Symptom of Feeling That Sight is Worsening | Intensity | 1.07 units on a scale | Standard Deviation 0.27 |
Primary
Symptom of Headache
Symptom of headache measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: One Month
Population: One subject score was not measured for Habitual spectacles group. Intensity of symptom of headache was measured only for subjects who had frequency of symptom of headache on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Headache | Frequency | 0.33 units on a scale | Standard Deviation 0.48 |
| Comfilcon A Asphere | Symptom of Headache | Intensity | 1.22 units on a scale | Standard Deviation 0.44 |
| Habitual Spectacles | Symptom of Headache | Frequency | 0.54 units on a scale | Standard Deviation 0.58 |
| Habitual Spectacles | Symptom of Headache | Intensity | 1.14 units on a scale | Standard Deviation 0.36 |
Primary
Symptom of Headache
Symptom of headache measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Baseline
Population: Intensity of symptom of headache was measured only for subjects who had frequency of symptom of headache on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Headache | Frequency | 0.72 units on a scale | Standard Deviation 0.63 |
| Comfilcon A Asphere | Symptom of Headache | Intensity | 1.10 units on a scale | Standard Deviation 0.3 |
| Habitual Spectacles | Symptom of Headache | Frequency | 0.69 units on a scale | Standard Deviation 0.6 |
| Habitual Spectacles | Symptom of Headache | Intensity | 1.06 units on a scale | Standard Deviation 0.24 |
Primary
Symptom of Headache
Symptom of headache measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Two Months
Population: Intensity of symptom of headache was measured only for subjects who had frequency of symptom of headache on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Headache | Frequency | 0.30 units on a scale | Standard Deviation 0.47 |
| Comfilcon A Asphere | Symptom of Headache | ntensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Headache | Frequency | 0.55 units on a scale | Standard Deviation 0.51 |
| Habitual Spectacles | Symptom of Headache | ntensity | 1.13 units on a scale | Standard Deviation 0.34 |
Primary
Symptom of Heavy Eyelids
Symptom of heavy eyelids measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Baseline
Population: Intensity of symptom of heavy eyelids was measured only for subjects who had frequency of symptom of heavy eyelids on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Heavy Eyelids | Frequency | 0.56 units on a scale | Standard Deviation 0.62 |
| Comfilcon A Asphere | Symptom of Heavy Eyelids | Intensity | 1.13 units on a scale | Standard Deviation 0.34 |
| Habitual Spectacles | Symptom of Heavy Eyelids | Frequency | 0.45 units on a scale | Standard Deviation 0.51 |
| Habitual Spectacles | Symptom of Heavy Eyelids | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Heavy Eyelids
Symptom of heavy eyelids measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Two Months
Population: Intensity of symptom of heavy eyelids was measured only for subjects who had frequency of symptom of heavy eyelids on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Heavy Eyelids | Frequency | 0.35 units on a scale | Standard Deviation 0.49 |
| Comfilcon A Asphere | Symptom of Heavy Eyelids | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Heavy Eyelids | Frequency | 0.48 units on a scale | Standard Deviation 0.63 |
| Habitual Spectacles | Symptom of Heavy Eyelids | Intensity | 1.08 units on a scale | Standard Deviation 0.29 |
Primary
Symptom of Heavy Eyelids
Symptom of heavy eyelids measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: One Month
Population: One subject score was not measured for Habitual spectacles group. Intensity of symptom of heavy eyelids was measured only for subjects who had frequency of symptom of heavy eyelids on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Heavy Eyelids | Frequency | 0.39 units on a scale | Standard Deviation 0.5 |
| Comfilcon A Asphere | Symptom of Heavy Eyelids | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Heavy Eyelids | Frequency | 0.46 units on a scale | Standard Deviation 0.58 |
| Habitual Spectacles | Symptom of Heavy Eyelids | Intensity | 1.17 units on a scale | Standard Deviation 0.39 |
Primary
Symptom of Increased Sensitivity to Light
Symptom of increased sensitivity to light measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Baseline
Population: Intensity of symptom of increased sensitivity to light was measured only for subjects who had frequency of symptom of increased sensitivity to light on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Increased Sensitivity to Light | Frequency | 0.59 units on a scale | Standard Deviation 0.67 |
| Comfilcon A Asphere | Symptom of Increased Sensitivity to Light | Intensity | 1.19 units on a scale | Standard Deviation 0.4 |
| Habitual Spectacles | Symptom of Increased Sensitivity to Light | Frequency | 0.48 units on a scale | Standard Deviation 0.63 |
| Habitual Spectacles | Symptom of Increased Sensitivity to Light | Intensity | 1.17 units on a scale | Standard Deviation 0.39 |
Primary
Symptom of Increased Sensitivity to Light
Symptom of increased sensitivity to light measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: One Month
Population: One subject score was not measured for Habitual spectacles group. Intensity of symptom of increased sensitivity to light was measured only for subjects who had frequency of symptom of increased sensitivity to light on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Increased Sensitivity to Light | Frequency | 0.25 units on a scale | Standard Deviation 0.44 |
| Comfilcon A Asphere | Symptom of Increased Sensitivity to Light | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Increased Sensitivity to Light | Frequency | 0.36 units on a scale | Standard Deviation 0.62 |
| Habitual Spectacles | Symptom of Increased Sensitivity to Light | Intensity | 1.13 units on a scale | Standard Deviation 0.35 |
Primary
Symptom of Increased Sensitivity to Light
Symptom of increased sensitivity to light measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Two Months
Population: Intensity of symptom of increased sensitivity to light was measured only for subjects who had frequency of symptom of increased sensitivity to light on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Increased Sensitivity to Light | Frequency | 0.10 units on a scale | Standard Deviation 0.31 |
| Comfilcon A Asphere | Symptom of Increased Sensitivity to Light | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Increased Sensitivity to Light | Frequency | 0.24 units on a scale | Standard Deviation 0.44 |
| Habitual Spectacles | Symptom of Increased Sensitivity to Light | Intensity | 1.14 units on a scale | Standard Deviation 0.38 |
Primary
Symptom of Itching
Symptom of itching measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Two Months
Population: Intensity of itching was measured only for subjects who had frequency of itching on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Itching | Frequency | 0.45 units on a scale | Standard Deviation 0.51 |
| Comfilcon A Asphere | Symptom of Itching | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Itching | Frequency | 0.41 units on a scale | Standard Deviation 0.5 |
| Habitual Spectacles | Symptom of Itching | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Itching
Symptom of itching measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: One Month
Population: One subject score was not measured for Habitual spectacles group. Intensity of itching was measured only for subjects who had frequency of itching on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Itching | Frequency | 0.68 units on a scale | Standard Deviation 0.55 |
| Comfilcon A Asphere | Symptom of Itching | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Itching | Frequency | 0.36 units on a scale | Standard Deviation 0.56 |
| Habitual Spectacles | Symptom of Itching | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Itching
Symptom of itching measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Baseline
Population: Intensity of itching was measured only for subjects who had frequency of itching on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Itching | Frequency | 0.41 units on a scale | Standard Deviation 0.56 |
| Comfilcon A Asphere | Symptom of Itching | Intensity | 1.08 units on a scale | Standard Deviation 0.29 |
| Habitual Spectacles | Symptom of Itching | Frequency | 0.52 units on a scale | Standard Deviation 0.57 |
| Habitual Spectacles | Symptom of Itching | Intensity | 1.00 units on a scale | Standard Deviation 0 |
Primary
Symptom of Tearing
Symptom of tearing measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Two Months
Population: Intensity of symptom of tearing was measured only for subjects who had frequency of symptom of tearing on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Tearing | Frequency | 0.35 units on a scale | Standard Deviation 0.49 |
| Comfilcon A Asphere | Symptom of Tearing | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Tearing | Frequency | 0.45 units on a scale | Standard Deviation 0.57 |
| Habitual Spectacles | Symptom of Tearing | Intensity | 1.08 units on a scale | Standard Deviation 0.29 |
Primary
Symptom of Tearing
Symptom of tearing measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: Baseline
Population: Intensity of symptom of tearing was measured only for subjects who had frequency of symptom of tearing on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Tearing | Frequency | 0.53 units on a scale | Standard Deviation 0.51 |
| Comfilcon A Asphere | Symptom of Tearing | Intensity | 1.06 units on a scale | Standard Deviation 0.24 |
| Habitual Spectacles | Symptom of Tearing | Frequency | 0.43 units on a scale | Standard Deviation 0.63 |
| Habitual Spectacles | Symptom of Tearing | Intensity | 1.18 units on a scale | Standard Deviation 0.4 |
Primary
Symptom of Tearing
Symptom of tearing measured by frequency on a scale of 0-2 (0-never, 1- occasionally, 2- often/always) and intensity on a scale of 1-2 (1- moderate 2- intense).
Time frame: One Month
Population: One subject score was not measured for Habitual spectacles group. Intensity of symptom of tearing was measured only for subjects who had frequency of symptom of tearing on a scale of 1 - occasionally and 2- often/always
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| Comfilcon A Asphere | Symptom of Tearing | Frequency | 0.39 units on a scale | Standard Deviation 0.57 |
| Comfilcon A Asphere | Symptom of Tearing | Intensity | 1.00 units on a scale | Standard Deviation 0 |
| Habitual Spectacles | Symptom of Tearing | Frequency | 0.33 units on a scale | Standard Deviation 0.48 |
| Habitual Spectacles | Symptom of Tearing | Intensity | 1.10 units on a scale | Standard Deviation 0.32 |