Optimizing the Approach of Mobile Application Use to Improve Medication Adherence in Patients With Hypertension

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04066010

Enrollment

Registered

2019-08-22

Start date

2016-10-31

Completion date

2018-11-30

Last updated

2019-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension, Medication Adherence

Brief summary

The purpose of this study was to determine the effectiveness of using a custom-designed mobile application to improve blood pressure (BP) and promote adherence to antihypertensive medication regimens. This was a prospective, multicenter, randomized controlled trial. Patients were randomized to an intervention or control group for three months. Antihypertensive medication refill history was assessed three months before, during and three months after the study period. Continuous outcome measures investigated were systolic/diastolic BP and medication refill history, using the cumulative medication gap (CMG) score.

Interventions

OTHERMobile application (BP-n-Me)

The mobile app consisted of a series of features including (1) calendar reminders of when to take medications and the patient's antihypertensive medication regimen (2) a Call your Pharmacist button specific to patient's pharmacy, (3) a BP log in which the patient could enter blood pressure values that were automatically compared to goal values, (4) counseling points for lifestyle and adherence factors individually tailored to each patient and (5) lifestyle and medication adherence surveys.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

OTHER

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* 18 years of age * Diagnosed with hypertension as evidenced by diagnosis codes or chart documentation * Prescribed at least one antihypertensive for a minimum of three months prior to enrollment * Have access to an Android mobile device with data capabilities * Consent to using the application on their device

Exclusion criteria

* Do not read or speak English * Unable to read and sign the informed consent or Health Insurance Privacy and Accountability Act (HIPAA) waiver * Too ill or cognitively impaired to participate

Design outcomes

Primary

Measure	Time frame	Description
Medication adherence	6 months	This was assessed based on cumulative medication gap (CMG)
Blood pressure	6 months	This was assessed by measuring the change of systolic and diastolic blood pressure

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026