Cardiac Resynchronization Therapy, Reduced Biventricular Pacing, Systolic Heart Failure, Ventricular Premature Complexes, Ventricular Tachycardia
Conditions
Brief summary
Cardiac resynchronization therapy reduces mortality in patients with systolic heart failure and left bundle branch block. Reduced biventricular pacing can lead to therapy failure. Most effective mortality reduction was seen with a BiV pacing above 98%. Reduced BiV pacing is a common phenomenon with potential impact on CRT-response and pts' prognosis. Frequent ventricular ectopy may be associated with attenuated benefit from CRT. The investigators sought to systematically assess the effect of ventricular arrhythmia treatment on BiV pacing.
Interventions
PROCEDURECatheter ablation of ventricular arrhythmia
PVC or VT ablation
DRUGIntensified medical therapy
Dosage increase / new onset of Betablocker / medical antiarrhythmic medication according to guideline and clinical practice
Sponsors
Universitätsklinikum Köln
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* reduced biventricular pacing \<98% due to ventricular arrhythmia
Exclusion criteria
* reduced biventricular pacing \<98% due to other cause * age \<18 * pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Percentage of Biventricular pacing | 3 month after intervention biventricular pacing (%) is routinely monitored | Influence of intervention (Ablation/medical treatment) on previously reduced biventricular pacing percentage (\<98%). Biventricular pacing is measured in percentage of stimulation and is monitored at routine device interrogation. |
Countries
Germany
Outcome results
None listed