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Exercise Training as Medicine for Substance Use Disorder Patients

Effects of Low- Versus High Dose High Intensity Interval Training and Strength Training on Physical Health in Substance Use Disorder Patients: A Randomized Controlled Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04065334
Enrollment
171
Registered
2019-08-22
Start date
2020-02-01
Completion date
2023-12-11
Last updated
2025-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Substance Use Disorders

Keywords

Resistance training, Endurance training

Brief summary

This study compares the effects of high dose and low dose, high intensity, endurance training and strength training in substance use disorder patients. The hypothesis is that the increase in endurance (measured as maximal oxygen uptake) and strength (measured as maximal strength) will be similar in both the high dose and low dose training groups after 24 training sessions over eight weeks. The rationale for this assumption is based on the patient groups poor physical capacity, supporting that a lesser physical workload is needed to achieve a substantial increase in physical capacity. The practical implication could be higher training attendance, because it is likely easier to motivate the patient group when they only have to perform half the workload. It is paramount for this patient group to increase their physical capacity and consequently augment their physical health status since they are in a high-risk group for developing life-threatening lifestyle related diseases.

Interventions

BEHAVIORALHigh dose training

4 x 4 minutes of high intensity workload on treadmill and 4 repetitions x 4 sets of high intensity workload in hack squat

BEHAVIORALlow dose training

1 x 4 minutes of high intensity workload on treadmill and 2 repetitions x 4 sets of high intensity workload in hack squat

Sponsors

Norwegian University of Science and Technology
CollaboratorOTHER
St. Olavs Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Being an inpatient at the clinic * Free of known cardiovascular disease, pulmonary disease and cancer

Exclusion criteria

* Not able to perform a maximal treadmill test * Not able to perform a maximal strength test in hack squat

Design outcomes

Primary

MeasureTime frameDescription
change in oxygen uptakebaseline to 8 weekscardiopulmonary exercise test (CPET) objective gas measurements
change in leg muscular strengthbaseline to 8 weeksOne repetition maximum strength test half squat

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 11, 2026