Skip to content

Analysis of the Capnography Curve Can Allow the Discrimination of Obstructive Patients - Modeling the Capnography Curve

Analysis of the Capnography Curve Can Allow the Discrimination of Obstructive Patients - Modeling the Capnography Curve

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04064580
Acronym
CAPNOBST
Enrollment
300
Registered
2019-08-22
Start date
2019-11-30
Completion date
2021-07-31
Last updated
2019-10-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive Syndrome, Respiratory Pathology

Keywords

capnography

Brief summary

Obstructive respiratory diseases such as asthma or COPD are a common reason for emergency room visits. Currently, nasal gill capnography and oxygen saturation measurement (SpO2) are the only two non-invasive means of continuously monitoring a respiratory pathology. To date, Respiratory Functional Explorations (CFE) and more particularly spirometry, are considered as the reference examinations for the diagnosis or monitoring of asthma or COPD. However, physical and physical constraints make their use almost impossible in the context of the emergency with patients presenting to emergencies in respiratory distress, often require oxygen therapy or even non-invasive ventilation. Only pulmonary auscultation can make the diagnosis of acute decompensation of obstructive pathology. This technique is qualitative and imprecise, sometimes leading to a diagnostic uncertainty resulting in delay in taking charge and inappropriate therapy. Studies have shown a change in the capnography curve in obstructive airway disorder and a strong correlation between some capnography parameters and spirometry parameters such as the Tiffeneau ratio (FEV1 / FVC), suggesting capnography as a simple and effective technique for the diagnosis of obstructive syndrome of patients in emergencies.

Interventions

OTHERdiagnostic test

performing a capnography examination

Sponsors

University Hospital, Strasbourg, France
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Major patient male or female * Patient with respiratory disease with and without obstructive syndrome or patient without respiratory pathology * Patient requiring spirometry breathing functional exploration * Subject affiliated to a social health insurance scheme * Subject able to understand the objectives and the risks related to the research and to give its non opposition

Exclusion criteria

* Pregnant and lactating woman * Patient not affiliated to a social protection scheme * Subject in exclusion period (determined by previous or current study), * Impossibility of giving the subject information enlightened (subject in emergency situation, difficulties of understanding the subject, ...) * Subject under the protection of justice Subject under guardianship or curatorship

Design outcomes

Primary

MeasureTime frameDescription
Spirometry measurement1 dayTiffenau Report Compendium (FEV1 / FVC) and FEV1 for spirometry (gold standard defining presence of obstructive disorder). Collection of the capnography curves of each patient allowing in a second time to perform an analysis of the curve by different methods.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026