Acupuncture Treatment for Improving Alzheimer's Dementia

Clinical Trial to Measure Efficacy of Acupuncture Treatment for Alzheimer's Dementia as Measured by MOCA(Montreal Cognitive Assessment)

Status

Withdrawn

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04064021

Enrollment

Registered

2019-08-21

Start date

2025-01-01

Completion date

2027-03-31

Last updated

2022-10-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer Disease, Cognitive Deficits

Keywords

Acupunture

Brief summary

Evaluate cognitive improvement pre amd post acupuncture treatment in patients with probable alzheimer's dementia as measured by MOCA score and also per form A( measure of patient's personal information). Also caregiver input.

Detailed description

Patient's with diagnosis of probable mild to moderate AD will be enrolled in this study. Patient will undergo neurological examination including MOCA. Examiner will also fill out Form A at the time of initial evaluation. Patient will then undergo series of acupuncture treatments 2 per week for 6 weeks(12 acupuncture treatment). At end of this intervention patients will be reassessed using same testing(MOCA and form A) Data collected will be assessed via statistical analysis to see if there is any statistically significant improvement. Acupuncture points used in this trial will stay the same for all subjects and throughout the course. The points will be Si Shen Chong, ST36, 37, LV 2,3,6, GB 34, 39, Xia San Huang, LI 11, LI 4.

Interventions

PROCEDUREAcupunture

Patient will receive 12 acupuncture treatments over 6 weeks (2x per week)

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

60 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Mild to moderate AD

Exclusion criteria

* Severe AD

Design outcomes

Primary

Measure	Time frame	Description
Improvement on Montreal Cognitive Assessment test of 5 points or more than baseline( total score is out of 30 points)	12 weeks	Subject will complete 3 MOCA assessment prior to study over 1 week time. Best score of three is used. After study is complete subject will also undergo 3 MOCA assessment over 1 week immediately after study. Again best score is used.

Secondary

Measure	Time frame	Description
Improvement of Montreal Cognitive Assessment test by category than raw total score	12 weeks	performance on various subcategory will also be reviewed to see if one category improves over other category. (Example: Visual-spacial parameters improves over language)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026