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Cyanoacrylate With Sutures for Fixation of Free Gingival Graft

Cyanoacrylate Tissue Adhesive Assisted Soft Tissue Stabilization: a Novel Technique for Free Gingival Graft Fixation (Case Series Study)

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04063475
Enrollment
10
Registered
2019-08-21
Start date
2019-09-16
Completion date
2020-06-30
Last updated
2019-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Soft Tissue Atrophy

Brief summary

fixation of FGG with sutures alone is not sufficient,we use cyanoacrylate beside sutures for fixation

Detailed description

Inadequate zone of attached mucosa around implants, gingival recession, inadequate ridge width or height despite there is enouph bone for implant placement are problems that face periodontists and can be treated by soft tissue graft Studies have demonstrated the importance of the tissues stability for the first hours when support is provided by underlying osseous or dental structures. Movement of the graft during mastication and phonation will disturb healing procedures. Most of the clinicians prefer a protective device during the healing phase. Transitional dentures are not stable themselves, and hence are not suitable for stabilizing. Circummandibular wiring and impact posts are seemingly very aggressive for patients and need extra clinical practices, skills, and equipment. Studies proved that the maximum tissue shrinkage (approximately 20%-40%) occurs during the first 3 months post operation and will proceed until 12 postsurgical months with a persistent, significantly lower rate. In this study we give more stabilization for free gingival grafts by using cyanoacrylate tissue adhesive beside sutures Its autogenous character, maintenance of keratinization, predictability, ease of technique tlead CTG to be accepted as the golden standard to increase attached gingival dimensions Cyanoacrylate is a simple, inexpensive haemostatic and biocompatible material It is used as tissue adhesives in paediatric surgery general surgery and also dentistry. it has been applied intraorally with different purposes such as periodontal dressing,for sealing sinus membrane perforations for stabilizing bone fragments during fracture fixation, and in closing peripheral nerve anastomosis it seems promising in the intraoral field due to their strong sealing, bacteriostatic, and hemostatic properties. Multiple studies examined the use of cyanoacrylate glues as an alternative to suturing intraoral and extraoral wounds concluding that cyanoacrylates are faster, more reliable ,and less painful and cause better hemostasis .

Interventions

using cyanoacrylate tissue adhesive for FGG fixation

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE

Intervention model description

Cyanoacrylate beside sutures for Fixation of FGG

Eligibility

Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* Patients with hopeless teeth that need extraction * Age: between 20 and 60 years * Both sexes. * Subjects willing to sign an informed consent form ,participate in the study and return for follow-up visits

Exclusion criteria

* • Patients with coagulation disorders (Hemophilia a/b, von Willebrand disease, liver disease, anticoagulative therapy), * patients on corticosteroids, * patients with uncontrolled diabetes mellitus * smokers * Pregnant or lactating mother. * Known systemic diseases and/ or drug therapy which may interfere with wound healing or contraindicate periodontal therapy * Allergy to cyanoacrylate

Design outcomes

Primary

MeasureTime frameDescription
graft shrinkage in millimeter2 weeks,month,3monthsgraft area ,thickness in millimeter

Secondary

MeasureTime frameDescription
success percentage3 months% percentage (success of Free Gingival Graft Fixation)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026