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Development of a Predictive Index for Probable Depression Among Secondary School Students

A Longitudinal Study for Identifying Predictors of Incidence/Remission of Probable Depression and Developing a Predictive Index for Probable Depression Among Secondary School Students

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04063202
Enrollment
4799
Registered
2019-08-21
Start date
2020-10-30
Completion date
2023-08-31
Last updated
2022-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression, Stress, Youth

Keywords

Adolescent, Depression, Stress, Resilience

Brief summary

The present study aims to develop a new predictive index to predict future depression of adolescents by using factors including individual, interpersonal and environmental. The index can be used to predict likelihood of students who are non-probable depression cases convert into probable depression cases. In addition, the investigators also test the factors of depression remission. It can hence be used in school setting to identify high-risk students, and provide them with secondary interventions that are designed by considering modifiable significant variables identified in this unique, large-scale, longitudinal study.

Detailed description

A 12-month longitudinal study will be conducted in secondary school settings. The investigators will investigate incidence of probable depression (i.e., from non-depression, CESD\<16, at baseline to probable depression, CESD≥16, at month 12) and remission of probable depression. The investigators will investigate factors that can prospectively predict new cases/remission of probable depression, including both well-documented risk/protective factors and some under-examined but potentially important local factors (e.g. school/academic stress, psychological resilience). The relative importance of the risk/protective factors at different socio-ecological levels will be compared and their combined effect will be identified. Based on the selected factors, the investigators will derive a new prediction index called the Adolescent Depression Prediction Index (ADPI) in a model building sample and test its performance in predicting incidence of depression in a validation sample among secondary school students in Hong Kong.

Interventions

OTHERObservation

The anonymous structured questionnaire will be self-administered by the participating students in the absence of their teachers in class-room settings.

Sponsors

Chinese University of Hong Kong
Lead SponsorOTHER

Study design

Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
12 Years to 16 Years
Healthy volunteers
No

Inclusion criteria

* Secondary 1 (seventh year of formal education) to Secondary 4 Chinese students, who are studying local mainstream schools in Hong Kong. * Able to read Chinese and speak either Cantonese or Mandarin.

Exclusion criteria

* Eligible students whose parents refuse to give consent to take part in the study.

Design outcomes

Primary

MeasureTime frameDescription
Incidence of probable depression12 monthsTo examine the incidence of probable depression from non-depression (CESD\<16) at baseline to probable depression (CESD\>=16) at month 12.
Adolescent Depression Prediction Index (ADPI)12 monthsTo develop a new prediction index ADPI and test test its performance in predicting incidence of depression.

Countries

Hong Kong

Contacts

Primary ContactXue Yang, PhD
sherryxueyang@cuhk.edu.hk+852 2252 8740

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026