Aspiration, Respiratory, Mechanical Ventilation Complication, Nursing Caries, Ventilator Associated Pneumonia
Conditions
Keywords
Intensive Care
Brief summary
The purpose of study is to determine effects of three different ET cuff pressure control on microaspiration of the stomach contents.
Detailed description
In the study, ET cuff pressure control will be provided with pilot balloon fingers (Control Group), intermittent with a manometer (Study Group 1) and continuously with a smart cuff manager (Study Group 2). To assess the effect of different ETT cuff pressure control on microaspiration of the stomach contents, the pepsin level will be measured during deep tracheal secretions. The samples will be examined in the first four hours after intubation, all secretions collected up to the 24th hour of intubation after first sample intake and all secretions collected between 24-48 hours after intubation. Pepsin level will be considered as positive for cut-off point. In addition, the effect of different ETT cuff pressures control on the incidence of VAP will be examined.
Interventions
DEVICESmart Cuff Manager
Participant will be attached to the smart cuff manager within 4 hours after intubation. They will remain attached during the first 48 hours of intubation in the intensive care unit
DEVICEManometer
Participant will be attached to the manometer within 4 hours after intubation. They will assess 3 times per day during the first 48 hours of intubation in the intensive care unit
Sponsors
The Scientific and Technological Research Council of Turkey
Afyonkarahisar Health Sciences University Hospital
Afyonkarahisar Health Sciences University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Volunteering of the patient or relatives who will participate in the study, * Patients who require mechanical ventilation support with endotracheal tube supply for 48 hours.
Exclusion criteria
* Patients who are contraindicated in giving a semi-fowler position, * Patients with enteral nutrition contraindications, * Patients connected to mechanical ventilators for more than 48 hours, * Patients with tracheostomy, * Patients admitted to ICU for gastroesophageal reflux disease, aspiration pneumonia or suspicion, * Nasal endotracheal intubation.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Microaspiration of Gastric Contents | From randomisation to 48 hours after intubation | The unintentional aspiration of very small amounts of gastric contents |
Countries
Turkey (Türkiye)
Outcome results
None listed