Post Abdominal Surgery
Conditions
Keywords
HFNC, conventional oxygen, EIT, diaphragm thickness
Brief summary
This study aims to compare diaphragm thickness, air lung distribution, and several clinical and laboratory parameters on post abdominal surgery patients with conventional oxygen therapy vs high-flow nasal cannula
Detailed description
Approval from Ethical Committee of Faculty of Medicine Universitas Indonesia was acquired prior conducting the study. Subjects were recruited using consecutive sampling method. Subjects underwent upper-abdominal surgery were screened. Eligible and consented subjects were randomized into intervention group (high-flow nasal cannula) and control group (conventional oxygen therapy). Subject and operation characteristics were recorded prior to intervention. Clinical parameters (vital signs, Borg Score, ICON) were recorded in 10 specific times. diaphragm thickness data using abdominal ultrasonography (USG) and air lung distribution data using Electrical Impedance Tomography were collected in 7 specific times while lactate and blood gas analysis were done 4 times.
Interventions
PROCEDUREHFNC; COT
HFNC: high-flow nasal cannula therapy COT: conventional oxygen therapy
Sponsors
Indonesia University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* patients from 18 - 65 yrs old, * American Society of Anaesthesia (ASA) status I-III, * BMI \< 30, patent airway, * Measurement of Exercise Tolerance before Surgery (METS) Score \> 4, * P-POSSUM score \<10%, * agreed to the study
Exclusion criteria
* uncooperative subjects, * DNR (do not resuscitate) patients, * patients with tracheostomy, pleural effusion, pneumothorax or pulmonary atelectasis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| diaphragm thickness | 2 months | diaphragm thickness are measured sequentially by abdominal ultrasonography (mm) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| partial 02 pressure | 2 months | partial 02 pressure were collected from arterial blood gas analysis (mmHg) |
| partial carbondioxyde pressure | 2 months | partial CO2 pressure were collected from arterial blood gas analysis (mmHg) |
| ICON | 2 months | ICON were measured to observe hemodynamic status |
| electrical impedance tomography (EIT) data | 2 months | measured data to assess lung ventilation volume and air distribution |
| heart rate | 2 months | measured from monitor (bpm) |
| mean arterial pressure | 2 months | measured from monitor (mmHg) |
| respiratory rate | 2 months | bpm |
| lactate | 2 months | lactate were measured from arterial blood |
Countries
Indonesia
Outcome results
None listed