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Building and Pilot Testing a Couples-based Smartphone Systems to Address Alcohol Use Disorder

Building and Pilot Testing a Couples-based Smartphone Systems to Address Alcohol Use Disorder

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04059549
Enrollment
68
Registered
2019-08-16
Start date
2020-11-17
Completion date
2021-09-29
Last updated
2025-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alcohol Use Disorder, Behavior, Addictive, Couples

Brief summary

This project will develop and pilot test a new smartphone-based system for AUD patients, their partners, and clinicians called PartnerCHESS. PartnerCHESS will integrate key features of ABCT and A-CHESS. PartnerCHESS will also include a Clinician Report to automatically alert clinicians of patients at risk of relapse and offer other information on how recovery is proceeding. The project has three specific aims: 1. Integrate A-CHESS with key features of ABCT to create PartnerCHESS to serve patients, partners, and clinicians. 2. Conduct a pilot test (a small randomized clinical trial) of PartnerCHESS to estimate effect size and refine the protocol, procedures, recruitment strategy, measurements, and operations for use in a large RCT. 3a. Decide whether to pursue an R01 application, and if so, 3b. plan for the R01.

Detailed description

Alcohol use disorder (AUD) is one of the most common substance use disorders. Yet only a small fraction of people who need treatment receive it, and most of them get only short-term support even though continuing care has been shown to be much more effective. Partner support can be critical to recovery, but many partners do not know how to support their partners' recovery or manage their own responses to it. Clinicians also lack evidence of the efforts patients are making toward recovery. Treating couples in which one member is recovering from AUD has been shown to be efficacious; in particular, Alcohol Behavioral Couples Therapy (ABCT) has shown positive outcomes. Still, ABCT has not been widely adopted, in part because of practical problems such as the stigma that goes with the partner needing to go to an addiction treatment agency to participate. A-CHESS is a smartphone-based system proven to substantially reduce relapse rates, but A-CHESS serves only the patient. This project will develop and pilot test a new smartphone-based system for AUD patients, their partners, and clinicians called PartnerCHESS. PartnerCHESS will integrate key features of ABCT and A-CHESS. PartnerCHESS will also include a Clinician Report to automatically alert clinicians of patients at risk of relapse and offer other information on how recovery is proceeding. The project has three specific aims: 1. Integrate A-CHESS with key features of ABCT to create PartnerCHESS to serve patients, partners, and clinicians. 2. Conduct a pilot test (a small randomized clinical trial) of PartnerCHESS to estimate effect size and refine the protocol, procedures, recruitment strategy, measurements, and operations for use in a large RCT. 3a. Decide whether to pursue an R01 application, and if so, 3b. plan for the R01. The project would engage 6 couples to help design PartnerCHESS, test its usability and give feedback on its utility. Once ready, the system would be tested by 34 other couples randomized to receive either PartnerCHESS + treatment as usual (TAU) or A-CHESS + TAU for a 6-month trial. The investigators will collect survey data at baseline, 2, 4, and 6 months and analyze it to see if a large clinical trial holds promise and, if so, produce an application to support a full-scale trial based on the technology developed and the research procedures employed in the pilot test. The study is important to public health because of the scope of the alcohol abuse and the potential of technology to improve the lives of both patients and partners. If successful, such technology could greatly broaden the reach and impact of AUD treatment in general and couples therapy in particular.

Interventions

BEHAVIORALPartnerCHESS

Patients randomized to the PartnerCHESS group will receive all A-CHESS services plus the following services from ABCT: Urge discussion. Daily EMAs will track preconditions for relapse (urges), review urge reduction options on PartnerCHESS, and encourage discussions between partners on the causes of and ways to reduce urges. Homework checklist. Tracks which interventions the couple is using/practicing, along with resources to help. Relapse plan. Monitoring and reminders of steps planned for relapse prevention. Reminders. Reminders to notice something positive in partner, of reasons to stay sober, to take meds, etc. Trigger identification and removal. During set-up, patient and partner enter triggers. PartnerCHESS will quiz couples on upcoming trigger events and remind them of ways to address each.

BEHAVIORALA-CHESS

A-CHESS control group

Sponsors

University of Massachusetts, Worcester
CollaboratorOTHER
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
CollaboratorNIH
University of Wisconsin, Madison
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

A total of 34 dyads were recruited. Patients and partners: * Must be 18 or older * Not have a mental or physical condition that limits smartphone use * Cannot have experienced serious Interpersonal Violence Intimate Partner Violence (IPV) in the index (therapy) relationship in the past year * Not have a history of schizophrenia Patients: * Must have a DSM-5 diagnosis of alcohol use disorder or meet NIAAA guidelines for risky drinking. * Have had at least one alcoholic drink in the last 6 months Partners: * Must be a spouse, or in a 6-month or longer committed romantic relationship * Willing to participate in the study

Design outcomes

Primary

MeasureTime frameDescription
Number of Participants With no Heavy Drinkingbaseline, 2, 4, and 6 monthsAt each time of measurement, a timeline follow-back interview was conducted for the past 60 days. Risky drinking day was be defined as greater than 4 drinks for men and greater than 3 drinks for women in 2 hours.
Percentage of Days With Heavy Drinkingbaseline, 2, 4, and 6 monthsAt each time of measurement, a timeline follow-back interview was conducted for the past 60 days.
Percentage of Days With Any DrinkingBaseline, 2, 4, 6 monthsAt each time of measurement, a timeline follow-back interview was conducted for the past 60 days.

Secondary

MeasureTime frameDescription
Perceptions of Family Environment - ConflictBaseline, 2, 4, 6 monthsDrinkers and partners both completed the 9-item Cohesion and 9-item Conflict scales from the Family Environment Scale. Responses were true/false statements, with higher scores indicating more cohesion or conflict. Possible scores range from 33 to 80.
Psychological Distressbaseline, 2, 4, and 6 monthsDrinkers' and partners' psychological distress was assessed by the OQ-45 scale. Response options range from 0-4, with items 1, 12, 13, 20, 21, 24, 31, 37, and 43 reversed; items are summed (i.e., a possible range of 0-180). High scores suggest distress (anxiety, depression, somatic problems, stress), difficulties in interpersonal relationships and social roles (e.g., work), and low quality of life, with scores of 63 or more indicating symptoms of clinical significance, and changes of 14 points or more considered reliable.
Peer SupportBaseline, 2, 4, 6 monthsPartners reported on the availability of peer support using the 5-item McTavish Bonding Scale. Response options ranged 1-5 for a total possible range of scores from 5-25; with higher scores suggesting more support.
Commitment to SobrietyBaseline, 2, 4, 6 monthsDrinkers completed the 5-item Commitment to Sobriety Scale. Response options ranged 1-5 for a total possible range of scores from 5-25; with higher scores suggesting more commitment.
Relationship Satisfactionbaseline, 2, 4, and 6 monthsDrinkers' and partners' relationship satisfaction was assessed by the Dyadic Adjustment Scale-Brief (DAS-7) plus item 32 from the DAS-32. Response options ranged 0-5 on most items and 0-6 on item 7 of the DAS-7 (possible scores range from 0 to 41). Consistent with scoring instructions for the DAS-7, items were summed, with higher scores indicating more satisfaction.
Perceptions of Family Environment - CohesionBaseline, 2, 4, 6 monthsDrinkers and partners both completed the 9-item Cohesion and 9-item Conflict scales from the Family Environment Scale. Responses were true/false statements, with higher scores indicating more cohesion or conflict. Possible scores range from 4 to 65.

Countries

United States

Participant flow

Participants by arm

ArmCount
A-CHESS Drinker
Patients randomized to the A-CHESS group will receive the A-CHESS app on a smartphone. A-CHESS: A-CHESS control group
15
PartnerCHESS Drinker
Patients randomized to the PartnerCHESS group will receive all A-CHESS services listed above, plus learning modules and resources from Alcohol-based Couple Therapy. PartnerCHESS: Patients randomized to the PartnerCHESS group will receive all A-CHESS services plus the following services from ABCT: Urge discussion. Daily EMAs will track preconditions for relapse (urges), review urge reduction options on PartnerCHESS, and encourage discussions between partners on the causes of and ways to reduce urges. Homework checklist. Tracks which interventions the couple is using/practicing, along with resources to help. Relapse plan. Monitoring and reminders of steps planned for relapse prevention. Reminders. Reminders to notice something positive in partner, of reasons to stay sober, to take meds, etc. Trigger identification and removal. During set-up, patient and partner enter triggers. PartnerCHESS will quiz couples on upcoming trigger events and remind them of ways to address each.
18
A-CHESS Partner
Participants randomized to the A-CHESS group will receive the A-CHESS app on a smartphone. A-CHESS: A-CHESS control group
15
PartnerCHESS Partner
Participants randomized to the PartnerCHESS group will receive all A-CHESS services listed above, plus learning modules and resources from Alcohol-based Couple Therapy. PartnerCHESS: Patients randomized to the PartnerCHESS group will receive all A-CHESS services plus the following services from ABCT: Urge discussion. Daily EMAs will track preconditions for relapse (urges), review urge reduction options on PartnerCHESS, and encourage discussions between partners on the causes of and ways to reduce urges. Homework checklist. Tracks which interventions the couple is using/practicing, along with resources to help. Relapse plan. Monitoring and reminders of steps planned for relapse prevention. Reminders. Reminders to notice something positive in partner, of reasons to stay sober, to take meds, etc. Trigger identification and removal. During set-up, patient and partner enter triggers. PartnerCHESS will quiz couples on upcoming trigger events and remind them of ways to address each.
18
Total66

Withdrawals & dropouts

PeriodReasonFG000FG001
Overall StudyWithdrawal by Subject20

Baseline characteristics

CharacteristicTotalA-CHESS DrinkerPartnerCHESS DrinkerA-CHESS PartnerPartnerCHESS Partner
Age, Continuous39.97 years
STANDARD_DEVIATION 11.3
43.33 years
STANDARD_DEVIATION 12.43
37.83 years
STANDARD_DEVIATION 10.53
40.93 years
STANDARD_DEVIATION 12.4
38.50 years
STANDARD_DEVIATION 10.27
Alcohol use disorder severity (DSM-5)
Mild 2-3
1 Participants1 Participants0 Participants0 Participants0 Participants
Alcohol use disorder severity (DSM-5)
Moderate 4-5
2 Participants2 Participants0 Participants0 Participants0 Participants
Alcohol use disorder severity (DSM-5)
Severe 6+
30 Participants12 Participants18 Participants0 Participants0 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
3 Participants2 Participants1 Participants0 Participants0 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
63 Participants13 Participants17 Participants15 Participants18 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants0 Participants0 Participants0 Participants0 Participants
Living with partner55 Participants12 Participants15 Participants12 Participants16 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants0 Participants0 Participants0 Participants0 Participants
Race (NIH/OMB)
Asian
1 Participants0 Participants0 Participants1 Participants0 Participants
Race (NIH/OMB)
Black or African American
6 Participants1 Participants2 Participants0 Participants3 Participants
Race (NIH/OMB)
More than one race
6 Participants2 Participants2 Participants2 Participants0 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants0 Participants0 Participants0 Participants0 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants0 Participants0 Participants0 Participants0 Participants
Race (NIH/OMB)
White
53 Participants12 Participants14 Participants12 Participants15 Participants
Sex/Gender, Customized
Female
33 Participants3 Participants4 Participants13 Participants13 Participants
Sex/Gender, Customized
Male
32 Participants12 Participants13 Participants2 Participants5 Participants
Sex/Gender, Customized
Prefer not to say
1 Participants0 Participants1 Participants0 Participants0 Participants

Adverse events

Event typeEG000
affected / at risk
EG001
affected / at risk
deaths
Total, all-cause mortality
0 / 300 / 36
other
Total, other adverse events
0 / 300 / 36
serious
Total, serious adverse events
0 / 300 / 36

Outcome results

Primary

Number of Participants With no Heavy Drinking

At each time of measurement, a timeline follow-back interview was conducted for the past 60 days. Risky drinking day was be defined as greater than 4 drinks for men and greater than 3 drinks for women in 2 hours.

Time frame: baseline, 2, 4, and 6 months

ArmMeasureGroupValue (COUNT_OF_PARTICIPANTS)
A-CHESS DrinkerNumber of Participants With no Heavy DrinkingBaseline1 Participants
A-CHESS DrinkerNumber of Participants With no Heavy Drinking2 months1 Participants
A-CHESS DrinkerNumber of Participants With no Heavy Drinking4 months5 Participants
A-CHESS DrinkerNumber of Participants With no Heavy Drinking6 months6 Participants
PartnerCHESS DrinkerNumber of Participants With no Heavy Drinking6 months13 Participants
PartnerCHESS DrinkerNumber of Participants With no Heavy DrinkingBaseline2 Participants
PartnerCHESS DrinkerNumber of Participants With no Heavy Drinking4 months10 Participants
PartnerCHESS DrinkerNumber of Participants With no Heavy Drinking2 months5 Participants
Primary

Percentage of Days With Any Drinking

At each time of measurement, a timeline follow-back interview was conducted for the past 60 days.

Time frame: Baseline, 2, 4, 6 months

ArmMeasureGroupValue (MEAN)Dispersion
A-CHESS DrinkerPercentage of Days With Any DrinkingBaseline72.8 percentage of daysStandard Deviation 33.5
A-CHESS DrinkerPercentage of Days With Any Drinking2 months58.3 percentage of daysStandard Deviation 38.9
A-CHESS DrinkerPercentage of Days With Any Drinking4 months48.3 percentage of daysStandard Deviation 42.3
A-CHESS DrinkerPercentage of Days With Any Drinking6 months52.7 percentage of daysStandard Deviation 43.5
PartnerCHESS DrinkerPercentage of Days With Any Drinking6 months48.4 percentage of daysStandard Deviation 44.5
PartnerCHESS DrinkerPercentage of Days With Any DrinkingBaseline73.6 percentage of daysStandard Deviation 30
PartnerCHESS DrinkerPercentage of Days With Any Drinking4 months46.6 percentage of daysStandard Deviation 44.7
PartnerCHESS DrinkerPercentage of Days With Any Drinking2 months59.6 percentage of daysStandard Deviation 36.2
Primary

Percentage of Days With Heavy Drinking

At each time of measurement, a timeline follow-back interview was conducted for the past 60 days.

Time frame: baseline, 2, 4, and 6 months

ArmMeasureGroupValue (MEAN)Dispersion
A-CHESS DrinkerPercentage of Days With Heavy DrinkingBaseline51.7 percentage of daysStandard Deviation 38.4
A-CHESS DrinkerPercentage of Days With Heavy Drinking4 months34.9 percentage of daysStandard Deviation 40.5
A-CHESS DrinkerPercentage of Days With Heavy Drinking2 months46.7 percentage of daysStandard Deviation 39.4
A-CHESS DrinkerPercentage of Days With Heavy Drinking6 months37.4 percentage of daysStandard Deviation 44.6
PartnerCHESS DrinkerPercentage of Days With Heavy Drinking2 months28.6 percentage of daysStandard Deviation 28
PartnerCHESS DrinkerPercentage of Days With Heavy DrinkingBaseline50.3 percentage of daysStandard Deviation 34.7
PartnerCHESS DrinkerPercentage of Days With Heavy Drinking6 months17.7 percentage of daysStandard Deviation 31.7
PartnerCHESS DrinkerPercentage of Days With Heavy Drinking4 months18.2 percentage of daysStandard Deviation 29.2
Secondary

Commitment to Sobriety

Drinkers completed the 5-item Commitment to Sobriety Scale. Response options ranged 1-5 for a total possible range of scores from 5-25; with higher scores suggesting more commitment.

Time frame: Baseline, 2, 4, 6 months

ArmMeasureGroupValue (MEAN)Dispersion
A-CHESS DrinkerCommitment to SobrietyBaseline16.2 score on a scaleStandard Deviation 6.4
A-CHESS DrinkerCommitment to Sobriety2 months15.2 score on a scaleStandard Deviation 4.6
A-CHESS DrinkerCommitment to Sobriety4 months15.7 score on a scaleStandard Deviation 6.1
A-CHESS DrinkerCommitment to Sobriety6 months15.9 score on a scaleStandard Deviation 6.9
PartnerCHESS DrinkerCommitment to Sobriety6 months17.4 score on a scaleStandard Deviation 5.7
PartnerCHESS DrinkerCommitment to SobrietyBaseline15.9 score on a scaleStandard Deviation 4.7
PartnerCHESS DrinkerCommitment to Sobriety4 months17.8 score on a scaleStandard Deviation 4.7
PartnerCHESS DrinkerCommitment to Sobriety2 months15.1 score on a scaleStandard Deviation 6.2
Secondary

Peer Support

Partners reported on the availability of peer support using the 5-item McTavish Bonding Scale. Response options ranged 1-5 for a total possible range of scores from 5-25; with higher scores suggesting more support.

Time frame: Baseline, 2, 4, 6 months

ArmMeasureGroupValue (MEAN)Dispersion
A-CHESS DrinkerPeer SupportBaseline13.4 score on a scaleStandard Deviation 6.4
A-CHESS DrinkerPeer Support4 months11.5 score on a scaleStandard Deviation 4.8
A-CHESS DrinkerPeer Support2 months13.1 score on a scaleStandard Deviation 7.5
A-CHESS DrinkerPeer Support6 months12.9 score on a scaleStandard Deviation 5.7
PartnerCHESS DrinkerPeer Support6 months15.6 score on a scaleStandard Deviation 5.2
PartnerCHESS DrinkerPeer Support2 months16.1 score on a scaleStandard Deviation 3.8
PartnerCHESS DrinkerPeer Support4 months14.8 score on a scaleStandard Deviation 3.9
PartnerCHESS DrinkerPeer SupportBaseline10.8 score on a scaleStandard Deviation 4.2
Secondary

Perceptions of Family Environment - Cohesion

Drinkers and partners both completed the 9-item Cohesion and 9-item Conflict scales from the Family Environment Scale. Responses were true/false statements, with higher scores indicating more cohesion or conflict. Possible scores range from 4 to 65.

Time frame: Baseline, 2, 4, 6 months

ArmMeasureGroupValue (MEAN)Dispersion
A-CHESS DrinkerPerceptions of Family Environment - Cohesion6 months57.3 score on a scaleStandard Deviation 8.6
A-CHESS DrinkerPerceptions of Family Environment - Cohesion4 months58.6 score on a scaleStandard Deviation 8
A-CHESS DrinkerPerceptions of Family Environment - Cohesion2 months53.2 score on a scaleStandard Deviation 10.4
A-CHESS DrinkerPerceptions of Family Environment - CohesionBaseline54.9 score on a scaleStandard Deviation 11.8
PartnerCHESS DrinkerPerceptions of Family Environment - Cohesion2 months50.4 score on a scaleStandard Deviation 13.5
PartnerCHESS DrinkerPerceptions of Family Environment - Cohesion6 months54.8 score on a scaleStandard Deviation 15.9
PartnerCHESS DrinkerPerceptions of Family Environment - CohesionBaseline52.6 score on a scaleStandard Deviation 9.9
PartnerCHESS DrinkerPerceptions of Family Environment - Cohesion4 months54.8 score on a scaleStandard Deviation 14.6
A-CHESS PartnerPerceptions of Family Environment - CohesionBaseline52.6 score on a scaleStandard Deviation 10.5
A-CHESS PartnerPerceptions of Family Environment - Cohesion6 months57.2 score on a scaleStandard Deviation 12.8
A-CHESS PartnerPerceptions of Family Environment - Cohesion4 months56.4 score on a scaleStandard Deviation 11.8
A-CHESS PartnerPerceptions of Family Environment - Cohesion2 months52.3 score on a scaleStandard Deviation 12.6
PartnerCHESS PartnerPerceptions of Family Environment - Cohesion6 months50.7 score on a scaleStandard Deviation 17.4
PartnerCHESS PartnerPerceptions of Family Environment - Cohesion2 months50.7 score on a scaleStandard Deviation 13.4
PartnerCHESS PartnerPerceptions of Family Environment - Cohesion4 months55.2 score on a scaleStandard Deviation 9.9
PartnerCHESS PartnerPerceptions of Family Environment - CohesionBaseline47.4 score on a scaleStandard Deviation 15.8
Secondary

Perceptions of Family Environment - Conflict

Drinkers and partners both completed the 9-item Cohesion and 9-item Conflict scales from the Family Environment Scale. Responses were true/false statements, with higher scores indicating more cohesion or conflict. Possible scores range from 33 to 80.

Time frame: Baseline, 2, 4, 6 months

ArmMeasureGroupValue (MEAN)Dispersion
A-CHESS DrinkerPerceptions of Family Environment - ConflictBaseline46.2 score on a scaleStandard Deviation 14.2
A-CHESS DrinkerPerceptions of Family Environment - Conflict2 months40.6 score on a scaleStandard Deviation 12.3
A-CHESS DrinkerPerceptions of Family Environment - Conflict4 months40.6 score on a scaleStandard Deviation 9.8
A-CHESS DrinkerPerceptions of Family Environment - Conflict6 months42.3 score on a scaleStandard Deviation 13.2
PartnerCHESS DrinkerPerceptions of Family Environment - Conflict2 months45.3 score on a scaleStandard Deviation 11.3
PartnerCHESS DrinkerPerceptions of Family Environment - Conflict4 months43.4 score on a scaleStandard Deviation 11.7
PartnerCHESS DrinkerPerceptions of Family Environment - Conflict6 months43.6 score on a scaleStandard Deviation 10.5
PartnerCHESS DrinkerPerceptions of Family Environment - ConflictBaseline48.6 score on a scaleStandard Deviation 12.7
A-CHESS PartnerPerceptions of Family Environment - Conflict4 months43.8 score on a scaleStandard Deviation 10.6
A-CHESS PartnerPerceptions of Family Environment - Conflict2 months45.7 score on a scaleStandard Deviation 11
A-CHESS PartnerPerceptions of Family Environment - Conflict6 months43.1 score on a scaleStandard Deviation 8.7
A-CHESS PartnerPerceptions of Family Environment - ConflictBaseline47.1 score on a scaleStandard Deviation 12.4
PartnerCHESS PartnerPerceptions of Family Environment - Conflict6 months46.7 score on a scaleStandard Deviation 12.7
PartnerCHESS PartnerPerceptions of Family Environment - Conflict2 months45.4 score on a scaleStandard Deviation 11.3
PartnerCHESS PartnerPerceptions of Family Environment - ConflictBaseline52.8 score on a scaleStandard Deviation 13.1
PartnerCHESS PartnerPerceptions of Family Environment - Conflict4 months43.2 score on a scaleStandard Deviation 10.5
Secondary

Psychological Distress

Drinkers' and partners' psychological distress was assessed by the OQ-45 scale. Response options range from 0-4, with items 1, 12, 13, 20, 21, 24, 31, 37, and 43 reversed; items are summed (i.e., a possible range of 0-180). High scores suggest distress (anxiety, depression, somatic problems, stress), difficulties in interpersonal relationships and social roles (e.g., work), and low quality of life, with scores of 63 or more indicating symptoms of clinical significance, and changes of 14 points or more considered reliable.

Time frame: baseline, 2, 4, and 6 months

ArmMeasureGroupValue (MEAN)Dispersion
A-CHESS DrinkerPsychological DistressBaseline54.5 score on a scaleStandard Deviation 31.1
A-CHESS DrinkerPsychological Distress2 months51.7 score on a scaleStandard Deviation 29.5
A-CHESS DrinkerPsychological Distress4 months40.3 score on a scaleStandard Deviation 25
A-CHESS DrinkerPsychological Distress6 months48.8 score on a scaleStandard Deviation 25.3
PartnerCHESS DrinkerPsychological Distress2 months65.7 score on a scaleStandard Deviation 28.2
PartnerCHESS DrinkerPsychological Distress4 months59.7 score on a scaleStandard Deviation 27.4
PartnerCHESS DrinkerPsychological Distress6 months52.1 score on a scaleStandard Deviation 25.8
PartnerCHESS DrinkerPsychological DistressBaseline66.3 score on a scaleStandard Deviation 27.4
A-CHESS PartnerPsychological Distress4 months41.5 score on a scaleStandard Deviation 16.1
A-CHESS PartnerPsychological Distress2 months46.8 score on a scaleStandard Deviation 24.1
A-CHESS PartnerPsychological Distress6 months43.2 score on a scaleStandard Deviation 25.4
A-CHESS PartnerPsychological DistressBaseline44.5 score on a scaleStandard Deviation 23.4
PartnerCHESS PartnerPsychological Distress6 months54.8 score on a scaleStandard Deviation 29.1
PartnerCHESS PartnerPsychological Distress2 months53.0 score on a scaleStandard Deviation 20.8
PartnerCHESS PartnerPsychological DistressBaseline53.6 score on a scaleStandard Deviation 21.8
PartnerCHESS PartnerPsychological Distress4 months52.9 score on a scaleStandard Deviation 27.3
Secondary

Relationship Satisfaction

Drinkers' and partners' relationship satisfaction was assessed by the Dyadic Adjustment Scale-Brief (DAS-7) plus item 32 from the DAS-32. Response options ranged 0-5 on most items and 0-6 on item 7 of the DAS-7 (possible scores range from 0 to 41). Consistent with scoring instructions for the DAS-7, items were summed, with higher scores indicating more satisfaction.

Time frame: baseline, 2, 4, and 6 months

ArmMeasureGroupValue (MEAN)Dispersion
A-CHESS DrinkerRelationship SatisfactionBaseline28.4 score on a scaleStandard Deviation 4.1
A-CHESS DrinkerRelationship Satisfaction2 months27.9 score on a scaleStandard Deviation 4.3
A-CHESS DrinkerRelationship Satisfaction4 months30.0 score on a scaleStandard Deviation 4.4
A-CHESS DrinkerRelationship Satisfaction6 months29.4 score on a scaleStandard Deviation 5.9
PartnerCHESS DrinkerRelationship Satisfaction2 months27.0 score on a scaleStandard Deviation 8.1
PartnerCHESS DrinkerRelationship Satisfaction4 months28.1 score on a scaleStandard Deviation 7.7
PartnerCHESS DrinkerRelationship Satisfaction6 months27.4 score on a scaleStandard Deviation 7.9
PartnerCHESS DrinkerRelationship SatisfactionBaseline27.5 score on a scaleStandard Deviation 7.3
A-CHESS PartnerRelationship Satisfaction4 months27.1 score on a scaleStandard Deviation 6.2
A-CHESS PartnerRelationship Satisfaction2 months26.9 score on a scaleStandard Deviation 6.5
A-CHESS PartnerRelationship Satisfaction6 months27.5 score on a scaleStandard Deviation 6.6
A-CHESS PartnerRelationship SatisfactionBaseline27.4 score on a scaleStandard Deviation 6.8
PartnerCHESS PartnerRelationship Satisfaction6 months24.3 score on a scaleStandard Deviation 7.3
PartnerCHESS PartnerRelationship Satisfaction2 months26.5 score on a scaleStandard Deviation 7.7
PartnerCHESS PartnerRelationship SatisfactionBaseline27.6 score on a scaleStandard Deviation 6.4
PartnerCHESS PartnerRelationship Satisfaction4 months25.4 score on a scaleStandard Deviation 6.7

Source: ClinicalTrials.gov · Data processed: Feb 5, 2026