Cystic Fibrosis
Conditions
Keywords
cystic fibrosis, walk test
Brief summary
The aim of this study is to assess whether the 1 minute Sit to Stand (STS) test can be used as a measure of submaximal endurance during a pulmonary exacerbation of Cystic Fibrosis (CF) for patients in the acute care setting. We hypothesize that if the STS test is a valid measure of submaximal cardiovascular endurance, it will moderately correlate with 6 minute walk distance (6MWD).
Interventions
DIAGNOSTIC_TESTSit to stand test
Participants will complete a sit to stand test in addition to a 6 minute walk test
Sponsors
Boston Children's Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
6 Years to 35 Years
Healthy volunteers
No
Inclusion criteria
* patients age 6-35 with cystic fibrosis who are admitted for a pulmonary exacerbation and receive ongoing physical therapy throughout their admission.
Exclusion criteria
* patients with cystic fibrosis who are under the age of 6, * patients with cystic fibrosis who are not admitted for a pulmonary exacerbation, * patients with cystic fibrosis who are not being followed regularly by physical therapy (\>5x/week) throughout their inpatient admission, * patients with cystic fibrosis who are unable to follow instructions for standardized testing, * patients with cystic fibrosis who are not medically stable to participate in submaximal exercise testing. * patients whose inpatient admission is anticipated to be \<1 week. * Patients who are readmitted to the hospital within the year will not be included in the study more than once.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 6MWT power | 6 minutes | total distance in feet multiplied by bodyweight in pounds |
| 1-minute STS repetitions: | 1 minute | Number of STS completed |
| 1 minute STS power: | 1 minute | number of STS completed in 1 minute multiplied by bodyweight in pounds |
| 6 Minute Walk Distance (6MWD): | 6 minutes | total distance in feet completed during test |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Heart rate | 1 minute | beats per minute |
| Oxygen saturation | 1-6 minutes | percentage via pulse oximetry |
| Respiratory rate | 1-6 min | breaths per minute |
| Rating of perceived exertion | 6 minutes | rating via Borg scale for perceived exertion: 0-10 with 0 being no breathlessness and 10 being maximal breathlessness |
Countries
United States
Outcome results
None listed