Bacterial Vaginoses
Conditions
Keywords
Bacterial vaginosis, polymerase chain reaction, molecular diagnostic
Brief summary
. Treatment with dequalinium chloride vaginal tablets for 6 days had a cure rate lower than expected; only 37% of patients were considered cured one month after treatment.
Detailed description
This is the first study to utilize a molecular diagnostic test as a test of cure for bacterial vaginosis. The Nugent score is a reliable method for diagnosing bacterial vaginosis, but similar to traditional clinical diagnostic methods, it is not equally reliable when utilized as a test of cure. This study demonstrated that molecular diagnostic testing can be used as a test of cure and this is the first molecular test that can do that. Treatment with dequalinium chloride vaginal tablets for 6 days had a cure rate lower than expected; only 37% of patients were considered cured one month after treatment.
Interventions
DRUGD
treatment of BV with dequalinium chloride vaginal tablets
Sponsors
Skaraborg Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
BV
Exclusion criteria
No other infection (Gc, clhlamydia, trihomonas)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| cure rate of BV | 1 year | how many that are cured of BV after 1 month |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Diagnosis of BV using molecular test | 1 year | the Kappa index Hay/ison diagnosis and the molecular test |
Outcome results
None listed