Tonsillar Hypertrophy
Conditions
Brief summary
* Tonsillectomy is a common pediatric procedure for the treatment of sleep-disordered breathing and chronic tonsillitis. Up to half of children having this procedure experience a perioperative respiratory adverse event. * We tried to determine whether tulobuterol patch (transdermal bronchodilator) premedication decreases the risk of perioperative respiratory adverse events in children undergoing anesthesia for tonsillectomy.
Interventions
DRUGTulobuterol Hydrochloride
The appropriate time interval between the patch attachment and the end of surgery was within 8 to 10 hours.
The appropriate time interval between the patch attachment and the end of surgery was within 8 to 10 hours.
Sponsors
Samsung Medical Center
Chung-Ang University Hosptial, Chung-Ang University College of Medicine
Severance Hospital
Seoul National University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
3 Years to 6 Years
Healthy volunteers
No
Inclusion criteria
* pediatric patients undergoing tonsillectomy
Exclusion criteria
* recent upper respiratory infection (2weeks) * Allergy to tulobuterol patch * Patients receiving catecholamine (epinephrine, isoproterenol) * hyperthyroidism * hypertension * cardiac disease * Diabetes melitus * atopic dermatitis * Asthma
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| perioperative respiratory complication | from anesthetic induction to postanesthesia care unit discharge, an average of 3 hours | laryngospasm, bronchospasm, oxygen desaturation, airway obstruction, severe coughing, postoperative stridor |
Countries
South Korea
Outcome results
None listed