Stroke
Conditions
Keywords
cerebellar stroke, upper extremity rehabilitation robot, transcranial direct current stimulation, stroke rehabilitation
Brief summary
Effects of upper extremity rehabilitation robot and transcranial direct current stimulation on upper extremity function among subjects with tremor after stroke
Interventions
Combined transcranial direct current stimulation(tDCS) on-line and upper extremity rehabilitation robot for 5 times a week for 4 weeks
OTHERRobot and sham tDCS
Combined sham tDCS and upper extremity rehabilitation robot for 5 times a week for 4 weeks
Sponsors
National Rehabilitation Center, Seoul, Korea
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Stroke with cerebellar hemorrhage or infarction * ataxia or tremor on upper extremities secondary to stroke * Cognitively intact enough to understand and follow the instructions from the investigator
Exclusion criteria
* History of surgery of affected upper limb * Fracture of affected upper limb
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change of Scale for the assessment and rating of ataxia | Change of Scale for the assessment and rating of ataxia at 4 weeks after baseline compared to baseline | Change of Scale for the assessment and rating of ataxia |
| Change of Functional ataxia rating scale - upper limb | Change of the Functional ataxia rating scale - upper limb, at 4 weeks after baseline compared to baseline | Change of Functional ataxia rating scale - upper limb |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Jerk during reaching and finger pointing | baseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline | Kinematic data during reaching and finger pointing using Trakstar |
| Smoothness during reaching and finger pointing | baseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline | Kinematic data during reaching and finger pointing using Trakstar |
| Behavioral activation system/behavioral inhibition system scale | baseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline | In terms of motivation |
| Beck's depression index | baseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline | Beck's depression index |
| Stroke rehabilitation motivation scale | baseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline | Stroke rehabilitation motivation scale |
| Intrinsic motivation inventory | baseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline | Intrinsic motivation inventory |
| Numeric rating scale for upper extremity pain | baseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline | Question about the upper extremity pain (0-10; higher is better) |
| Fugl-Meyer Assessment - upper extremity | baseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline | Fugl-Meyer Assessment - upper extremity |
| modified Barthel index | baseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline | modified Barthel index |
| % maximal voluntary contraction from upper extremity muscles during reaching task | baseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline | data from surface electromyography from upper extremity muscles during reaching task |
| Kinematic data during scale for the assessment and rating of ataxia | baseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline | Kinematic data during scale for the assessment and rating of ataxia |
| Scale for the assessment and rating of ataxia | baseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline | Scale for the assessment and rating of ataxia |
| Functional ataxia rating scale - upper limb | baseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline | Functional ataxia rating scale - upper limb, kinematic data during scale for the assessment |
| Kinematic data during scale during the Functional ataxia rating scale - upper limb | baseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline | Kinematic data during scale during the Functional ataxia rating scale - upper limb |
| Functional reaching test | baseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline | Functional reaching test |
| Composite cerebellar functional severity score | baseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline | Composite cerebellar functional severity score (Nine hole peg test + click test) |
Countries
South Korea
Contacts
Primary ContactJoon-Ho Shin, MS
Outcome results
None listed