Cognitive Impairment, Traumatic Brain Injury
Conditions
Keywords
Traumatic Brain Injury, Cognitive Impairment, Intervention
Brief summary
The purpose of this research study is to investigate the effectiveness of a memory enhancement technique in persons with a Traumatic Brian Injury (TBI). The study is designed to research how well this technique can help people with TBI improve their memory and their ability to function better in everyday life
Detailed description
Impairments in higher level cognitive processing, such as new learning and memory, are common in Traumatic Brain Injury (TBI)and negatively impact multiple aspects of everyday life, including occupational and social functioning. Despite this, few studies have attempted to remediate these cognitive deficits in order to improve everyday functioning. While not applied in traditional rehabilitation protocols as of yet, many techniques from cognitive psychology significantly improve learning and memory in healthy persons. These techniques include the generation effect (GE), the spacing effect (SE), and the testing effect (TE). These techniques have recently been incorporated into an 8-session treatment protocol, Stylistic Memory Enhancement (SME), designed to teach participants about each of the techniques, train them on how to apply the techniques in daily life and practice their application to daily life memory demanding situations. The protocol includes teaching participants how to restructure a memory demanding situation in order to make optimal use of self-generation, spaced learning and self-testing.
Interventions
BEHAVIORALSME
The treatment group (TX) will complete 8 sessions of SME (2 sessions per week for 4 weeks), de-signed to teach the concepts of SG, SL and RP and the application of these techniques in daily life. Sessions are approximately 30-45 minutes long.
Sponsors
National Institute on Disability, Independent Living, and Rehabilitation Research
Kessler Foundation
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Masking description
Once enrolled, participants will be randomly assigned to the TX or CTL group via a computerized random number generator coordinated by the statistician, who will not be blinded. Group assignment will be concealed. Both the participant and the examiner conducting the baseline and outcome assessments will be blind to group membership.
Intervention model description
The purpose of this research study is to investigate the effectiveness of a memory enhancement technique in persons with a Traumatic Brian Injury (TBI).
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
In order to participate in this study I must meet the following requirements: * I am between the ages of 18-65. * I have had a traumatic brain injury (TBI) at least 1 year ago. * I can read and speak English fluently. * I have difficulties with learning and memory skills.
Exclusion criteria
* I have had a prior stroke or neurological injury/disease other than TBI. * I have a history of significant psychiatric illness (for example, bipolar disorder, schizophrenia, or psychosis) or a current diagnosis of Major Depressive Disorder, Schizophrenia, Bipolar Disorder I or II. * I have a significant alcohol or drug abuse history (inpatient Treatment). * I am taking certain medications that might exclude me from the research. The study team will review my medications with me.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Self Report Deficits in Daily Life | 5 weeks from baseline (short term follow-up) and 7 months from baseline (long term follow-up) | Perceived Deficits Questionnaire215 * •20 items; evaluates everyday situations in which cognition has a role * •Cronbach's Alpha (lower bound reliability) = .93 |
Countries
United States
Outcome results
None listed