COPD
Conditions
Brief summary
The pathophysiological characteristics of COPD is irreversible airflow restriction which may influence the gas exchange and cause the abnormal PaO2 and PaCO2. Assessment of the partial arterial pressure of carbon dioxide (PaCO2 ) is the 'gold standard' for the evaluation of the adequacy of alveolar ventilation.Method used mostly nowadays : arterial puncture which is accurate but is invasive 、painful、 non-dynamic and there is risk of infection and tissue、nerve damage. Noninvasive measurement methods (Most commonly used)： end-tidal CO2（ ETCO2）、 transcutaneous CO2(TcCO2). They all can monitor the PaCO2 dynamically、 noninvasively, but is existence of controversy of the accuracy. So the investigators want to compare the accuracy of these two noninvasive methods for assessment of PaCO2.
Interventions
None listed
Sponsors
The First Affiliated Hospital of Guangzhou Medical University
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
20 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* COPD patients
Exclusion criteria
* hemodynamics is unstable; * any other lung disease despite COPD； * other diseases influencing experiments: Cognitive impairment disease、 mouth and nose trauma.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| concordance between the values of PetCO2 and PaCO2 measured at the same time | 1 hour | concordance between the values of PetCO2 and PaCO2 measured at the same time |
| concordance between the values of PtcO2 and PaCO2 measured at the same time | 1 hour | concordance between the values of PtcO2 and PaCO2 measured at the same time |
Countries
China
Contacts
Primary ContactShanshan Zha, master
Outcome results
None listed