Stroke
Conditions
Brief summary
The aim of the present study is to evaluate the possible effect of using dual-tDCS applied during conventional physical therapy on lower limb function in stroke patients.
Detailed description
Recently dual-tDCS applied before the conventional physical therapy show positive effect of lower limb performance. However to explore the time during which dual-tDCS can be combined with physical therapy to maximize motor performance is required. Results from the present study with be compared with our previous study that used dual-tDCS applied before physical therapy.
Interventions
DEVICETranscranial direct current stimulation
Dual Active/sham tDCS will be applied over the leg motor area (M1) during the first 20 mins of conventional physical therapy. Anodal on affected hemisphere, Cathodal on unaffected hemisphere. Each participant will complete two experiments (active/sham tDCS). The interval between two experiments is at least 2 weeks. The two experiments will be performed in random order for each subject.
Sponsors
National Research Council of Thailand
Mahidol University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
1. Age range 18-75 years. 2. First ever-ischemic lesion in the territory of middle cerebral artery or anterior cerebral artery. CT scan/MRI result is thus required. 3. Sub acute phase of stroke (less than 6 months) 4. Able to sit-to-stand and stand-to-sit independently 5. Able to walk without physical assistance at least 6 m 6. Free of any neurological antecedent, unstable medical conditions or condition that may increase the risk of stimulation such as epilepsy
Exclusion criteria
1. Pre-stroke disability 2. Pregnant 3. Be unable to understand the instruction 4. No clear neurological antecedent history or psychiatric disorder 5. Excessive pain in any joint of the paretic limb (numerical pain rating score \> 7) 6. Presence of intracranial metal implantation, cochlea implant, or cardiac pacemaker 7. Subjects are participating in the other protocol or receiving alternative treatment such as acupuncture
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Five-Times-Sit-To-Stand test (FTSST) | 5 minutes | sling. Subjects will be instructed as the following I want you to stand up and sit down 5 times as quickly as you can when I say 'Go'. Subjects must be fully standing between repetitions. Timing will begin at GO and ends when the patient's buttocks touch the seat after the fifth sit-to-stand. |
| Timed Up & Go test (TUG) | 5 minutes | Subjects will sits on the chair and place their back against the chair. Timing will begin at GO, the subjects will be asked to walk 3m, turn, walk back, and sit down. The stopwatch stops when the patient's buttocks touch the seat. |
Countries
Thailand
Outcome results
None listed