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Simulation of Adenosine Push Methods for Treatment of SVT Using Agitated Saline Visualized by Ultrasound

Simulation of Adenosine Push Methods for Treatment of SVT Using Agitated Saline Visualized by Ultrasound

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04051541
Enrollment
20
Registered
2019-08-09
Start date
2019-05-06
Completion date
2019-06-28
Last updated
2023-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Supraventricular Tachycardia

Brief summary

Supraventricular tachycardia (SVT) is an abnormally fast heart rhythm arising from improper electrical activity in the upper part of the heart. SVT is commonly treated with adenosine using three different IV administration techniques. However, it is not well known which of these three techniques is the quickest or most likely to reach the heart in order to stop SVT. This study will simulate each of those techniques in an investigator-blinded procedure. Intravenous agitated saline, used as a surrogate for a dose of adenosine, will be administered to healthy volunteers using all three techniques and monitored using bedside ultrasound to observe their efficacy and speed in reaching the right side of the heart.

Interventions

OTHERAgitated saline push

Push of agitated saline to simulate adenosine used for supraventricular tachycardia

Sponsors

HealthPartners Institute
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE

Masking description

The investigator performing the ultrasound and the person timing the simulation were both blind to the method used for each push. An unblended investigator performed the pushes but did not assess the outcomes.

Intervention model description

This is a simulation study in which all participants receive a dose of agitated saline through an IV using three different administration methods.

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Volunteers aged 18 years and older * Able to understand and provide signed consent for the study * Must be healthy; not being actively treated for any condition that requires active medical intervention or monitoring to avert serious danger to the participant's health or well-being, as evaluated by study investigator

Exclusion criteria

* Non-English speaker * Those with contraindications to peripheral IV placement, such as infection or other contraindication noted from evaluation by study investigator * Pregnancy

Design outcomes

Primary

MeasureTime frameDescription
Time to ultrasound visualization of agitated saline in the right heart<5 secondsTime from IV push to ultrasound visualization of agitated saline in the right heart

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026