Breast Cancer Survivors, Cognitive Dysfunction
Conditions
Brief summary
This study will test whether a physical activity intervention can improve cognition in breast cancer survivors and help the development of physical activity guidelines for cognition in breast cancer survivors.
Detailed description
Many breast cancer survivors experience problems with mental abilities such as memory, attention, and concentration (known as cognition). Increasing physical activity has been shown to improve cognition in adults; however, little is known about whether this is helpful for cancer survivors as well. This study will test whether a physical activity intervention can improve cognition in breast cancer survivors and help the development of physical activity guidelines for cognition in breast cancer survivors.
Interventions
BEHAVIORALExercise
This intervention is based on Control Theory and Social Cognitive Theory and includes: 1) weekly emails with tips and tools to set personalized exercise goals and to increase exercise; 2) Health coaching phone sessions; 3) wrist worn monitor such as a Fitbit to track activity
BEHAVIORALControl
This intervention includes: 1) weekly emails with tips and tools to support health and wellness such as brain health, stress management, nutrition; 2) Health coaching phone sessions
Sponsors
University of California, San Diego
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
40 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* breast cancer survivors who have completed active treatment at least 6 months prior to enrollment and are within 5 years of diagnosis of stage 1, 2, or 3 breast cancer * self-report difficulties with cognition since their cancer diagnosis * self-report low levels of moderate to vigorous physical activity * have a Fitbit compatible device with internet * breast cancer was treated with chemotherapy and/or hormonal therapy
Exclusion criteria
* medical condition that could make it potentially unsafe to be in an unsupervised physical activity intervention * currently taking tamoxifen or aromatase inhibitor that will be stopped in the next 6 months * unable to commit to a 12-month study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| National Institutes of Health Toolbox - Cognition Domain - Oral Symbol Digital Test | Baseline to 6 months | Measure of processing speed |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| National Institutes of Health Toolbox - Cognition Domain - Oral Symbol Digital Test | Baseline to 12 months | Measure of processing speed |
| Patient Reported Outcomes Measurement Information System (PROMIS) cognitive abilities | Baseline to 6 months and Baseline to 12 months | Measure of Self-Report Cognition |
Countries
United States
Outcome results
None listed