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The Effects of Different Music Genres on Heart Rate Variability in Extremely and Very Low Birth Weight Newborns

The Effects of Different Music Genres on Heart Rate Variability in Extremely and Very Low Birth Weight Premature Newborns: An Italian Pilot Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04049526
Enrollment
30
Registered
2019-08-08
Start date
2019-02-01
Completion date
2019-06-30
Last updated
2026-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infant Behavior, Infant Conditions, Infant Morbidity

Keywords

Music, Preterm infants, Heart Rate Variability

Brief summary

AIM: to investigate the influence of different music genres on Heart Rate Variability (HRV) of preterm infants. Neonates undergo a daily randomized music listening program. An electrocardiogram is performed to evaluate HRV parameters in each neonate with and without music exposure.

Detailed description

AIM: to investigate the influence of different music genres on Heart Rate Variability (HRV) of preterm infants. HRV has been previously used to evaluate autonomic nervous system fluctuations in heart rate related to maturation in healthy neonates and in neonates with pathological conditions. This parameter has been used to show how music could improve well-being and the development of the autonomic nervous system in infants. In this study, neonates (see also inclusion/exclusion criteria), recruited on the basis of birth order, undergo a daily randomized music listening program (25 minutes, every day, for 3 days) based on different music genres listening (soft pop-rap, pop-rock and classical music). Music programs is followed by 1 day of no music monitoring (25 minutes). An electrocardiogram is performed to evaluate HRV parameters in each neonate with and without music exposure.

Interventions

BEHAVIORALThe influence of different music genres on Heart Rate Variability (HRV) in preterm infants

Neonates undergo a daily randomized music listening program (25 minutes, every day, for 3 days) based on different music genres listening (soft pop-rap, pop-rock and classical music). Music programs is followed by 1 day of no music monitoring (25 minutes). An electrocardiogram is performed to evaluate HRV parameters in each neonate with and without music exposure

Sponsors

Ospedale di Circolo - Fondazione Macchi
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
1 Days to 90 Days
Healthy volunteers
No

Inclusion criteria

* gestational age between the 23th and the 32nd week * birth weight \<1500g * appropriate for gestational age, sufficient stability of the vital parameters and absence of active infections and episodes of apnoea during the 72 hours before the test

Exclusion criteria

* genetic anomalies, chromosomal aberrations, congenital heart malformations, intraventricular haemorrhage (\> grade II on ultrasound), periventricular Leukomalacia * neonates with failed responses to bilateral hearing screening performed by Automated Auditory Brainstem Response testing

Design outcomes

Primary

MeasureTime frameDescription
Heart Rate Variability (HRV) variation in preterm infants according to different music genres listeningEnrollment performed when sufficient stability of the vital parameters and absence of active infections and episodes of apnoea during the 72 hours before the treatmentAn electrocardiogram is performed to evaluate HRV parameters in each neonate with and without music exposure.

Countries

Italy

Contacts

PRINCIPAL_INVESTIGATORBarbara Sgobbi

Tincontro Onlus

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 27, 2026