Chronic Rhinosinusitis (Diagnosis), Surgery
Conditions
Brief summary
Enhanced recovery after surgery (ERAS) protocols have been widely applied during perioperative periods for different diseases, there are few reports of ERAS in patients undergoing endoscopic sinus surgery (ESS). This study therefore aimed to evaluate the benefits of ERAS protocol compared to traditional care following ESS.
Interventions
One kind of NSAIDs, 200mg for 48 hours after surgery.
DRUGSufentanil
One kind of opioid drugs, 1.5μg/kg, and recorded the drug consumption after surgery
BEHAVIORALExtended perioperative counseling
The extended perioperative counseling contained additional information, including surgery procedures, importance of medicine treatment and medical help to relieve depression and anxiety about disease during peri-operation period.
BEHAVIORALShorter fasting food and water time before surgery
The patients in ERAS group were required to fast food for 6 to 8 hours and provided 12.6% maltodextrin carbohydrate supplement beverage for 2 hours before surgery
BEHAVIORALConventional perioperative counseling
THe conventional perioperative counseling included the risk of surgery and prognosis of disease and other things patients need to know.
BEHAVIORALRegular fasting food and water time before surgery
The stricter control of preoperative fasting requirements, prohibiting solids and liquids from previous midnight to operation time.
Sponsors
Beijing Tongren Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Intervention model description
Patients with chronic rhinosinusitis undergoing ESS were prospectively assigned to one of five groups; ERAS groups with postoperative intravenous Flubiprofen Axetil or analgesia pump, traditional care with Flubiprofen Axetil or analgesia pump (NERAS groups), or traditional care without postoperative intravenous analgesia group (control).
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* The patient has CRSwNP need endoscopic sinus surgery for treatment.
Exclusion criteria
* age under 18 years * pregnant * ASA grade IV * received oral or topical steroids within 4 weeks preceding surgery * had previous ESS history * intolerant to NSAIDS * comorbidity of severe mental disease * not compliant with therapy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain management | at 2 hours after surgery | The pain scores after surgery were scored on a visual analogue scale of 0 to 10 as previously described, with 0 being no complaints whatsoever and 10 being the worst imaginable. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Hunger scores | at 5 minutes before surgery start | The hunger scores before surgery were scored on a visual analogue scale of 0 to 10 as previously described, with 0 being no complaints whatsoever and 10 being the worst imaginable. |
| Self-rating Anxiety Scale | at baseline and 72 hours after surgery | The anxiety scale was measured by Self-rating Anxiety Scale (SAS) questionaire. The SAS questionaire contain 20 items and each item is range 1 to 4 points. The total scores is reported, which range 20 to 80 points and higher scores mean that more anxiety. |
| thirst scores | at 5 minutes before surgery start | The thirst scores before surgery were scored on a visual analogue scale of 0 to 10 as previously described, with 0 being no complaints whatsoever and 10 being the worst imaginable. |
| General comfort scores | at baseline and 72 hours after surgery | Kolcaba General Comfort Questionnaire (GCQ) was assessed to evaluate the quality of life of patients. The GCQ questionaire contain 28 items and each item is range 1 to 4 points. The total scores is reported, which range 28 to 112 points and higher scores mean that feel more comfort. |
| quality of sleeping | at baseline and 72 hours after surgery | Medical Outcomes Study Sleep Scale (MOS-SS) was assessed to evaluate the quality of sleep of patients. The MOS-SS questionaire contain 7 items, including sleep disturbance, snoring, awakening short of breath or with headache, sleep adequacy, daytime somnolence and amount of sleeping. |
Countries
China
Outcome results
None listed