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Risk Factors and Impact of Anesthesia Techniques on Myocardial Infarction Following Transurethral Resection of the Prostate

Risk Factors and Impact of Anesthesia Techniques on Myocardial Infarction Following Transurethral Resection of the Prostate: a Nationwide Database Case Control Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04047329
Enrollment
115025
Registered
2019-08-06
Start date
1998-01-01
Completion date
2016-03-22
Last updated
2019-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia, Myocardial Infarction, Transurethral Resection of Prostate Syndrome

Brief summary

This study examined the risk factors and the influence of the type of anesthetic used during transurethral resection of the prostate (TURP) on subsequent incidence of myocardial infarction (MI).

Detailed description

This study utilized a population-based, nationwide dataset to evaluate the risk factors of MI for patients with benign prostate hypertrophy (BPH) who received TURP. Besides, The study also compared the different effects of general anesthesia (GA) and neuraxial anesthesia (NA) on the incidence of MI within 6 and 12 months after TURP.

Interventions

OTHERgeneral anesthesia or neuraxial anesthesia

Sponsors

Chang Gung Memorial Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL

Inclusion criteria

* Patients receiving TURP surgery (1998-2012)

Exclusion criteria

* Patients without anesthesia records * Patients receiving both general and neuraxial anesthesia * Mortality within 12 months of TURP

Design outcomes

Primary

MeasureTime frameDescription
Number of patients with pre-operative diagnosed asthma developing post-TURP myocardial infarctionwithin 6 months after the first admission for TURPWe analyze pre-operative diagnosed asthma rate in patients who had myocardial infarction after the surgery of TURP.
Number of patients with pre-operative diagnosed heart disease history developing post-TURP myocardial infarctionwithin 6 months after the first admission for TURPWe analyze pre-operative diagnosed heart disease rate in patients who had myocardial infarction after the surgery of TURP.
Number of patients with pre-operative diagnosed stroke history developing post-TURP myocardial infarctionwithin 6 months after the first admission for TURPWe analyze pre-operative diagnosed stroke rate in patients who had myocardial infarction after the surgery of TURP.
Number of patients with pre-operative diagnosed liver cirrhosis history developing post-TURP myocardial infarctionwithin 6 months after the first admission for TURPWe analyze pre-operative diagnosed liver cirrhosis rate in patients who had myocardial infarction after the surgery of TURP.
Number of patients with pre-operative diagnosed chronic obstructive pulmonary disease developing post-TURP myocardial infarctionwithin 6 months after the first admission for TURPWe analyze pre-operative diagnosed chronic obstructive pulmonary disease rate in patients who had myocardial infarction after the surgery of TURP.
Postoperative myocardial infarctionwithin 6 months after the first admission for TURPPatients experienced myocardial infarction after transurethral resection of the prostate (TURP)
Patient's age (year-old) that developed post-TURP myocardial infarctionwithin 6 months after the first admission for TURPWe analyze age distribution of patients with post-TURP myocardial infarction
Number of patients with pre-operative diagnosed Diabetes Mellitus developing post-TURP myocardial infarctionwithin 6 months after the first admission for TURPWe analyze pre-operative diagnosed Diabetes Mellitus rate in patients who had myocardial infarction after the surgery of TURP.
Number of patients with pre-operative diagnosed disorders of lipoid metabolism developing post-TURP myocardial infarctionwithin 6 months after the first admission for TURPWe analyze pre-operative diagnosed disorders of lipoid metabolism rate in patients who had myocardial infarction after the surgery of TURP.
Number of patients with pre-operative diagnosed gout developing post-TURP myocardial infarctionwithin 6 months after the first admission for TURPWe analyze pre-operative diagnosed gout rate in patients who had myocardial infarction after the surgery of TURP.
Number of patients with pre-operative diagnosed hypertension developing post-TURP myocardial infarctionwithin 6 months after the first admission for TURPWe analyze pre-operative diagnosed hypertension rate in patients who had myocardial infarction after the surgery of TURP.

Secondary

MeasureTime frameDescription
Number of patients who had post-operative myocardial infarction after receiving neuraxial anesthesia for TURPwithin 6 months after the first admission for TURPNumber of patients who had post-operative myocardial infarction after receiving neuraxial anesthesia for TURP
Number of patients who did not have post-operative myocardial infarction after receiving general anesthesia for TURPwithin 12 months after the first admission for TURPNumber of patients who did not have post-operative myocardial infarction after receiving general anesthesia for TURP
Number of patients who did not have post-operative myocardial infarction after receiving neuraxial anesthesia for TURPwithin 12 months after the first admission for TURPNumber of patients who did not have post-operative myocardial infarction after receiving neuraxial anesthesia for TURP
Number of patients who had post-operative myocardial infarction after receiving general anesthesia for TURPwithin 6 months after the first admission for TURPNumber of patients who had post-operative myocardial infarction after receiving general anesthesia for TURP

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026