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Photobiomodulation and Root Resorption

Placebo-Controlled, Randomized, Double Blind Trial of Effect of Photobiomodulation Therapies On The Root Resorption Associated With Orthodontic Forces: A Pilot Study Using Micro Computed Tomography

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04044989
Enrollment
30
Registered
2019-08-05
Start date
2018-01-10
Completion date
2018-12-13
Last updated
2019-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orthodontic Appliance Complication, Orthodontic Pathological Resorption of External Root, Orthodontic Tooth Movement

Keywords

photobiomodulation, laser, LED, resorption, micro-CT

Brief summary

Objectives: The aim of this study is to investigate the effect of photobiomodulation therapies on root resorption compared with the placebo group. Materials and Methods: 30 patients, who were admitted to the …………. University Faculty of Dentistry Orthodontics Department for treatment, with an indication of upper right 1st premolar tooth extraction was included. Before the individuals' orthodontic treatment, 0.022 slot MBT brackets and tubes were placed on the maxillary 1st premolar and molar. A 150g buccal tipping force was applied to the 1st premolar. Individuals were then randomly divided into 3 groups. For the first group; laser application was performed with a 810 nm GaAlAs laser device at 0,3,7,14,21 and 28 days to 8 J/cm2. Second group; an LED application according to the manufacturer's instructions with a 850 nm wavelength and 20 mW/cm2 output power for 10 minutes per day during the experiment. Third group; a placebo therapy was completed whereby a laser device that did not make active pulses was used. At the end of four weeks, the amount of root surface resorption was compared using micro-CT imaging after the extraction of the teeth.

Interventions

DEVICELaser

Diode laser device was used for photobiomodulation

DEVICElight-emitting diode (LED)

LED device was used for photobiomodulation

DEVICEPlacebo

Diode laser device was used for placebo effect

Sponsors

University of Gaziantep
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
15 Years to 17 Years
Healthy volunteers
Yes

Inclusion criteria

* No history of orthodontic treatment * No systemic disease or craniofacial anomaly * No dental trauma and tooth with root resorption * Having good oral hygiene * No periodontal disease (no more than 3mm pocket) * No restored or endodontically untreated upper right 1st premolar teeth * Having the maxillary right 1st premolar tooth extraction indication of orthodontic treatment

Exclusion criteria

* Problems in patient compliance * Inadequate oral hygiene * Development of any medical problem making orthodontic treatment contraindicated during the study period

Design outcomes

Primary

MeasureTime frameDescription
Root Resorptionthrough study completion, an average of 4 weeksCrater volume measurement

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026