Renal Insufficiency
Conditions
Brief summary
The investigators hypothesize that the Systolic Foot-to-Apex Time Interval (SFATI) method will be accurate for measurement of systolic blood pressure with marked arterial stiffness as seen in patients with severe renal impairment. Also that the presence of arterial calcifications only changes the agreement between the SFATI method and the reference method (auscultatory method) if the calcifications are very severe.
Interventions
DIAGNOSTIC_TESTSystolic blood pressure
Systolic blood pressure measured by Foot-to-Apex Systolic Interval, conventional oscillometric measurement, and the auscultatory method
Sponsors
Technology Transfer Accelerator Offices _ SATT AxLR
Centre Hospitalier Universitaire de Nīmes
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* The patient must have given their free and informed consent and signed the consent form * The patient must be a member or beneficiary of a health insurance plan * Patient under consultation in the Nephrology for severe renal impairment (defined by a glomerular filtration rate \<30 mL / min, assessment within previous 3 months)
Exclusion criteria
* The subject is participating in an interventional study, or is in a period of exclusion determined by a previous study * The subject refuses to sign the consent * It is impossible to give the subject informed information * The patient is under safeguard of justice or state guardianship * Patient is pregnant or breastfeeding
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Systolic blood pressure according to oscillometric curve | Day 0 | mmHg measured by Systolic Foot-to-Apex Time Interval |
| Systolic blood pressure according to Korotkov sounds | Day 0 | mmHg measured by auscultatory method |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Brachial artery calcium score | Day 0 | Measured by ultrasound of the arteries of the upper limb |
| Presence of arterial rigidity | Day 0 | Yes/No, measured by Complior \> 10 m/s |
| Brachial pulse wave velocity | Day 0 | m/s |
| Modification of antihypertensive treatment to maintain systolic tension between 110 and 130 mm Hg | Day 0 | Change in antihypertensive treatment following measurement |
| Disease-associated patient characteristics | Day 0 | Age, sex, diabetes, Chronic Renal Disease stage |
| Systolic blood pressure according to conventional oscillometric measurement | Day 0 | mmHg; Dinamap |
Countries
France
Outcome results
None listed