Clinical Effect of Preventive Use of Tylenol on Fever After Removal of Drainage Tube in Lumbar Fusion Surgery

Randomized Controlled Study of Fever Probability, Risk Factors and Preventive Use of Non-steroidal Anti-inflammatory Drugs on Fever After Removal of Drainage Tube After Lumbar Fusion

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04042948

Enrollment

183

Registered

2019-08-02

Start date

2019-06-24

Completion date

2019-12-30

Last updated

2021-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Radiculopathy

Keywords

lumbar spinal stenosis, lumbar fusion surgery, drainage tube, removal of drainage tube, fever, prevention of fever, preventive use of non-steroidal inflammatory drug

Brief summary

This study evaluates the influence of Non-steroidal Anti-inflammatory Drugs on preventing fever after the removal of drainage tube in the patients who suffered lumbar fusion surgery, if the outcome turn out positive, the preventive use of non-steroidal anti-inflammatory drugs could decrease the possibility of fever happening when we remove the tube.

Interventions

DRUGTylenol

when we decide to remove the drainage tube, we ask the patient to take a pill of tylenol, and another pill in 12h later

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Subject)

Masking description

Randomized control parallel

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* adult patient * diagnosis of lumbar spinal stenosis * perform decompression and fusion surgery and lay a drainage tube * understand the test and could sign the name

Exclusion criteria

* beside the inclusion criteria

Design outcomes

Primary

Measure	Time frame	Description
the rate of fever after the removal of drainage tube	24 hours	we test the temperature of the patient in 24h after the removal of tube, we define fever if the temperature is higher than 37.8 degree

Secondary

Measure	Time frame	Description
the level of WBC	24 hours	we compare the change of the level of WBC of two groups in 24h after the removal of the drainage tube
the level of CRP	24 hours	we compare the change of the level of CRP of two groups in 24h after the removal of the drainage tube
the level of ESR	24 hours	we compare the change of the level of ESR of two groups in 24h after the removal of the drainage tube
the temperature	24 hours	we compare the change of the level of temperature of two groups in 24h after the removal of the drainage tube

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026