Peri-Implantitis, Peri-implant Mucositis, Thin Gingiva
Conditions
Keywords
clinical research, Implant, Implantology, Prospective, Randomized controlled trial, Soft Tissue Grafting, Single-Tooth Implants
Brief summary
The present study aimed to increase the thickness of the gingiva and prevent possible crestal bone resorption by placing the CTG or T-PRF membrane under the mucosa immediately after the implant treatment in individuals with thin gingival phenotype. The null hypothesis was that T-PRF used simultaneously with implant placement can be considered an alternative to CTG.
Detailed description
Although connective tissue graft (CTG) is considered as the best technique for soft tissue augmentation, limited supply of donor tissue because of palatal vessels and nerves, and postoperative pain may require alternative methods. The purpose of this study is to reduce the crestal bone resorption around the implant site by augmenting the Peri-Implant Soft Tissue with T-PRF (titanium prepared platelet-rich fibrin) or CTG and to compare the effectiveness of the two techniques. Through simultaneous augmentation of the soft tissue by T-PRF or CTG, a total of 30 implants were implanted in 30 patients (12 males, 18 females) with a mean age of 38.4 years. In the test group, implants were placed in thin tissues and thickened with T- PRF membrane at the same time, while in the control group, implants were placed in thin tissues and thickened with CTG at the same time. During the surgery (T 0 ) and at postoperative 3 months (T 1 ), keratinised tissue width (KTW) and Peri-Implant soft tissue thickness (STT) were measured from three points: occlusal part of the alveolar crest (OAC), midbuccal mucosa level (MBML), and over 1 mm of mucogingival junction (MGJ1).
Interventions
PROCEDUREPlacement of Implants and Thickening Peri-Implant Mucosa with T-PRF
A total of 40 ml blood sample was collected from the antecubital vein of the patients' right or left arms with 10 ml injectors. 40 ml blood was transferred to a grade-IV titanium tube for the T-PRF group. The titanium tubes containing the blood samples were instantly centrifuged in a tabletop centrifuge at room temperature. The blood samples of the T-PRF group were centrifuged clockwise at 2700 RPM for 20 minutes. Subsequent to the centrifugation process, the clots of the T-PRF group were removed from the tubes with sterile tweezers, separated from the RBC base with scissors, and left for over 20 minutes on sterile woven gauze to release the serum slowly from the collected clots. The implants were placed in thin tissues, and the thickness of the thin tissues was simultaneously increased with T-PRF.
PROCEDUREPlacement of Implants and Thickening Peri-Implant Mucosa with CTG
The implants were placed in thin tissues, and the thickness of the thin tissues was simultaneously increased with CTG. Autogenous connective tissue graft was harvested according to a single incision technique.
Sponsors
Abant Izzet Baysal University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
29 Years to 49 Years
Healthy volunteers
Yes
Inclusion criteria
* patients older than 18 years, * thin gingiva biotype, * one missing tooth in the incisor, canine and premolar area and presence of two natural adjacent teeth * no bone increasing procedures prior to and during dental implant,
Exclusion criteria
* history of a bleeding disorder or on anticoagulant therapy, * immunocompromised state and debilitating disease, * smoking and alcoholism, * poor oral hygiene, * diabetes.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Peri-implant Soft Tissue Thickness | Change from baseline soft tissue thickness at 3 months | The measurement of soft tissue thickness at three points: occlusal part of the alveolar crest (OAC), midbuccal mucosa level (MBML), over 1 mm of mucogingival junction (MGJ1)\] |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Keratinised Tissue Width (KTW) | Change from baseline keratinised tissue width at 3 months | The measurement of the keratinised tissue width between the cover screw and the mucogingival junction. |
Countries
Turkey (Türkiye)
Outcome results
None listed