Parkinson's Disease
Conditions
Keywords
Dual task performance, Executive function, Transcrainal direct current stimulation (tDCS)
Brief summary
To investigate the effect of concurrent transcranial direct current stimulation and gait training on gait performance when doing the cognitive dual-task in people with Parkinson's Disease.
Interventions
OTHERActive tDCS plus gait training
Participants in experimental group will accept Active tDCS which combined with treadmill
OTHERSham tDCS plus gait training
Participants in control group will accept Sham tDCS which combined with treadmill
Sponsors
National Yang Ming Chiao Tung University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
50 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Diagnosed with idiopathic PD * Hoehn and Yahr stages I-III * Mini Mental Status Examination (MMSE) score ≧ 24 * Could walk 10m independently with or without gait aid
Exclusion criteria
* Concurrent medication likely to affect mental performance * tDCS contraindication * Significant neurological, vestibular, visual disorders or psychiatric illness * Musculoskeletal or cardiopulmonary disease * Sensory system pathology
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Dual-task walking performance | Change from baseline at 4 weeks | To evaluate gait parameters while doing dual-task walking |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Single walking performance | Change from baseline at 4 weeks | To evaluate gait parameters while doing single walking |
| Trail-making test A & B | Change from baseline at 4 weeks | To evaluate executive function |
| Stroop color and word test-Chinese version | Change from baseline at 4 weeks | To evaluate executive function |
| Digit span test | Change from baseline at 4 weeks | To evaluate executive function |
Contacts
Primary ContactYearu Yang, Ph.D
Outcome results
None listed