Caries,Dental
Conditions
Keywords
Ozone, Pits and fissures sealants, Prevention
Brief summary
Decay is a multifactorial infective degenerative disease of hard dental tissues, caused by Streptococcus mutans and Lactobacillus forming the bacterial biofilm of teeth surfaces. Decays generally evolve in fissures and pits of secondary molars. Pits and fissure sealants prevent decays if performed in two years from eruption. Ozone has bactericidal effect and remineralizing capacity on enamel. The aim of this study is to assess the effectiveness of ozone application before sealants in increasing their duration in time.
Interventions
DEVICEOzone
One minute of pretreatment with ozone by using the OzoneDTA device
OTHERPits and fissure sealants
cleansing of the occlusal surfaces with a nylon brush and polishing toothpaste; surface etching with 36% orthophosphoric acid for 30'', surface cleaning and drying for 30 '', application of the sealing material, polymerization for 60'';
Sponsors
IRCCS Burlo Garofolo
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Intervention model description
Splith mouth design
Eligibility
Sex/Gender
ALL
Age
6 Years to 16 Years
Healthy volunteers
No
Inclusion criteria
* first or second secondary molars to be sealed * possibility to isolate with rubber dam both the teeth involved * no clear signs of pigmentations * good general health
Exclusion criteria
* latex allergy * epilepsy or other severe neurological pathologies * psychiatric disease * excessive sensibility to electrical current * severe asthma * enamel disorders, such as amelogenesis imperfect, white spots, fluorosis or Molar Incisors Hypomineralization
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Sealants failure | 12 months after sealant | Frequency of sealed failure defined as presence of to one or more of these outcomes: Marginal fissure; Sealant fracture; Decay; Marginal pigmentations; Sealant detachment Evaluation of the relative frequency of the different causes of failure |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Sealants failure | 6 months after sealant | Frequency of sealed failure defined as presence of to one or more of these outcomes: Marginal fissure; Sealant fracture; Decay; Marginal pigmentations; Sealant detachment Evaluation of the relative frequency of the different causes of failure |
| Secondary decay in failed sealants | 6 months after sealant | Frequency of secondary decay in teeth with failed sealants |
Countries
Italy
Contacts
Primary ContactMilena Cadenaro, DDS,MSc,PhD
Backup ContactChiara Navarra, DDS,MSc,PhD
Outcome results
None listed