Drug Utilization Review
Conditions
Keywords
medication reviews, elderly, primary care
Brief summary
The study is a follow-up of a randomized controlled study performed in 2011-2012 with medication reviews in elderly patients in Sweden. Additional data about mortality and hospital admissions have been collected.
Detailed description
Background Drug-related problems among the elderly population are common and increasing. Multi-professional medication reviews (MR) have arisen as a method to optimize drug therapy for frail elderly patients. Research has not yet been able to show conclusive evidence of the effect of MRs on mortality or hospital admissions. Aim The aim of this study was to assess the impact of MRs' on hospital admissions and mortality after six and 12 months in a frail population of 369 patients in primary care in a randomized controlled study. Methods Patients were blindly randomized to an intervention group (receiving MRs) and a control group (receiving usual care). Descriptive data on mortality and hospital admissions at six and 12 months were collected. Survival analysis was performed for time to death and time to the first hospital admission within 12 months.
Interventions
OTHERMedication review
Multi-professional medication review
Sponsors
Region Skane
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
TRIPLE (Subject, Caregiver, Investigator)
Masking description
Closed envelopes
Intervention model description
Patients were blindly randomized to intervention or control group in 2011. This study is a follow-up with additional data collection for the included patient, a total of 369.
Eligibility
Sex/Gender
ALL
Age
75 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* age\>75 years, living in nursing homes or community-dwelling with municipality-provided care, with multi-dose drug dispensing
Exclusion criteria
* lack of multi-dose drug dispensing, living at home with no municipality-provided care, \<75 years old
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| hospital admission | six months | time to the first hospital admission |
| Survival analysis | six months | time to death |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| number of hospital admissions | six months | number of hospital admissions |
| mortality | six months | number of deaths |
Other
| Measure | Time frame | Description |
|---|---|---|
| number of drugs | base-line | number of drugs |
Outcome results
None listed