Periodontal Diseases
Conditions
Keywords
Periodontitis, MINST, Scaling and root planing, Split mouth, 3D analysis
Brief summary
Minimally invasive non-surgical therapy (MINST) is a new approach towards regeneration of deep periodontal defects. Important part of MINST procedure, besides usage of magnification loupes and piezo-electric devices seems to be the usage of special mini-curettes, originally mini-five and after mini-five of Hu-Friedy. So far only descriptive data about the clinical effects of such procedure are available and comparative studies that would include other treatment alternatives are lacking. Therefore, the aim of our study is, on split-mouth model, to compare the number of diseased sites (defined by probing depth ˃ 4 mm and bleeding on probing) after conventional non-surgical therapy and MINST with the usage of special mini-curettes. In addition, new 3D parameters obtained from 3D optical scanning will be developed for evaluation of volume changes of soft tissues.
Interventions
PROCEDUREMINST
For reducing the need of surgical treatment in patients with chronic periodontal disease, we will use specifically designed Hu-Friedy curettes mini five, micro mini five and after five together with piezoelectric device with thin and delicate tips that produce less periodontal trauma than usual Gracey curettes.
PROCEDUREConventional SRP
Scaling and root planing with conventional instruments.
Sponsors
University of Ljubljana
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Masking description
Evaluator different to care provider
Intervention model description
Split mouth - experimental and control side in the same individual Side selection will be randomized
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* periodontitis Stage III, grade B/C * at least 20 teeth * at least 9 teeth (excluding molars) in the upper jaw * without FPD, implants * without occlusal trauma signs * no pathology of endodontic origin * without chronic systemic diseases * no periodontal treatment in the last 6 months
Exclusion criteria
* poor oral hygiene (PI \> 20% at evaluation) * antibiotic treatment in the last 6 months or during the observation period * pregnant women, lactation, serious chronic systemic diseases, medication with known influence on periodontium or wound healing
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of diseased sites | 3 months, 6 months, 12 months | Difference in No of Sites with PPD (probing pocket depth) \> 4 mm and BOP (bleeding upon probing) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| PPD | 3 months, 6 months, 12 months | Average probing pocket depth |
| CAL | 3 months, 6 months, 12 months | Clinical attachment loss |
| REC | 3 months, 6 months, 12 months | Gingival recession |
| VOL | 1 week, 1 month, 3 months, 6 months, 12 months | Volumetric 3D differences evaluated by optical scanning |
Countries
Slovenia
Outcome results
None listed