Breast Augmentation, Inhalation Anesthesia, Quality of Recovery, Total Intravenous Anesthesia
Conditions
Brief summary
Among aesthetic or cosmetic surgeries, breast augmentation was the most frequently performed and the endoscopic transaxillary approach has become the preferred incision for Asian women. As breast augmentation must be performed under general anesthesia accompanied by its effects and potential complications, types of general anesthesia may affect the quality of recovery. Currently, the two most common techniques of general anesthesia are inhalation anesthesia (IH) and total intravenous anesthesia (TIVA). The effects of these types of general anesthesia on the quality of recovery have been investigated for numerous surgical procedures. However, no prior studies have analyzed different types of anesthesia used for performing transaxillary endoscopic breast augmentation. This prospective, parallel, randomized controlled study will evaluate the effects of inhalation anesthesia vs. total intravenous anesthesia on the quality of recovery in patients undergoing transaxillary endoscopic breast augmentation.
Interventions
DRUGDesflurane
Anesthesia is maintained by desflurane in an oxygen air mixture of 60/40%. If inadequate depth of anesthesia is observed, the end-expiratory concentration of desflurane would be increased.
DRUGPropofol
Anesthesia is maintained by propofol 100-200 μg/kg/min. If inadequate depth of anesthesia is observed, the rate of propofol infusion would be increased.
Sponsors
Chih-Cheng Hung
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
20 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Patients are appropriate for undergoing transaxillary endoscopic breast augmentation * Age between 20-65 years * Physical Status I or II as defined by the American Society of Anesthesiologists (ASA) Physical Status Classification System
Exclusion criteria
* Having difficulty reading or hearing * Diagnosed with addictive disorder * Diagnosed with psychiatric disorder * Physical Status III-VI as defined by the ASA Physical Status Classification System * Presence of acute infection or inflammatory condition (e.g., fever).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Quality of recovery, postoperative day one | On the 1st postoperative day | Quality of recovery is assessed by the 15-item Quality of Recovery (QoR-15) questionnaire. The total score of the 15-item QoR ranges from 0 to 150, and a higher score indicates a better outcome. |
| Quality of recovery, postoperative day two | On the 2nd postoperative day | Quality of recovery is assessed by the 15-item Quality of Recovery (QoR-15) questionnaire. The total score of the 15-item QoR ranges from 0 to 150, and a higher score indicates a better outcome. |
Countries
Taiwan
Outcome results
None listed