Leptospirosis
Conditions
Keywords
leptospirosis, hospitalization
Brief summary
COLEPT is a prospective interventional study that intends to better inform about leptospirosis, a neglected zoonotic infectious disease. During prospective follow-up of hospitalized acute leptospirosis cases, the participants will be assessed during 1 year for epidemiological, clinical, bacteriological and immunological data. Main intervention consists in blood sampling and biological bank constitution.
Interventions
OTHERBlood and urine sampling and blood banking
In routine management, blood and urine will be sampled for each patients and specific analyses carried out. Only blood samples will be banked.
Sponsors
Institut National de la Santé Et de la Recherche Médicale, France
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
1 Days to No maximum
Healthy volunteers
Yes
Inclusion criteria
* clinico-biological manifestations compatible with acute leptospirosis OR proven leptospirosis with serological testing or PCR * onset of symptoms within 21 days * participant benefits of health insurance
Exclusion criteria
* participant's refusal, or refusal from his relatives in case of major incapacity of the eligible participant precluding expression of his will (coma, stay in intensive care unit))
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| disease severity | 0 to 21 days after onset of symptoms | Rate of death or severe organ insuffisiency |
Countries
France
Contacts
PRINCIPAL_INVESTIGATORLoïc RAFFRAY, MD, PhD
CHU Reunion, INSERM, CNRS, IRD UMR PIMIT
Outcome results
None listed