Inadequate Preparation for Colonoscopy; Personalized Colonoscopy Preparation
Conditions
Brief summary
Adequate bowel preparation is one of the most important quality measures in colonoscopy. Previous studies identified several factors associated with inadequate bowel preparation (IBP). No study has attempted to assign a different regimen to patients based on the presence of risk factors for inadequate bowel preparation. The aim of the study is to check if a personalized bowel preparation regimen based on risk factors for IBP, will lead to an overall improvement in bowel preparation during colonoscopy.
Interventions
DRUGSodium Picosulfate / Magnesium Oxide / Citric Acid in two split doses + one dose of polyethylene glycol + two Bisacodyl tablets day before the procedure
Bowel preparation
Sponsors
Rambam Health Care Campus
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* previous IBP * concurrent medical conditions (e.g. diabetes, constipation) * medications (e.g. opioids and tricyclic antidepressants)
Exclusion criteria
* previous colonic resection * patients with IBD * active CRC * chronic kidney disease at any stage * congestive heart failure at any stage * liver cirrhosis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Improved bowel preparation | Index colonoscopy | Boston Bowel Preparation Scale at index colonoscopy will be measured. The grading is between 1 and 3 for each segment of colon (ascending, transverse, descending) where 1 is poor and 3 is excellent (subscale). The final score is between 3 and 9 summing up the scores for each segment. |
Countries
Israel
Contacts
Primary ContactKlein, MD
Outcome results
None listed