Spinal Cord Injuries
Conditions
Brief summary
Lower extremity (LE) function of patients with a spinal cord injury (SCI) will be assessed in an observational project with a cross-sectional and a longitudinal study design. The main goal is to identify kinematic and kinetic parameters to precisely characterize LE function and in parallel the impairment and limitation in SCI patients throughout rehabilitation in acute patients and in chronic patients to define LE function and LE recovery.
Interventions
None listed
Sponsors
University of Zurich
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
- Patients: * Age 18-80 * Written informed consent * General consent * Spinal cord injury (SCI) * ASIA A-D injury with lowest extent of lesion between C1 and Th12 * Mini-Mental stat examintation score \> 26
Exclusion criteria
- Patients: * Inability to undertake any component of the trial protocol * Clinically significant conditions such as severe cardiovascular, pulmonary or malignant disease * Pure cauda equina i.e. peripheral nerve injury Inclusion Criteria - Healthy controls: * Age 18-80 * Written informed consent * General consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Kinematic movement analysis recorded with a motion capture system | Cross-sectional part: one measurement timepoint for patients with chronic SCI within 2 weeks after inclusion (chronic is defined as > 6 months after injury) | Kinematic movement variables crucial for recovery in lower extremity function after SCI are monitored throughout rehabilitation to generate complex and sensitive profiles of the neurological and functional recovery |
Countries
Switzerland
Outcome results
None listed