Healthy Adults, Healthy Aging
Conditions
Keywords
Brain Stimulation, Transcranial direct current stimulation, Motor function
Brief summary
The purpose of this study is to compare the effects of individualized brain stimulation based on simulation and conventional brain stimulation in healthy adults.
Interventions
Based on tDCS stimulation, individualized stimulation during 30 minutes with sitting position.
Conventional tDCS stimulation during 30 minutes with sitting position.
Sponsors
Samsung Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
19 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
• Healthy adult men and women without history of central nervous system disease and abnormalities
Exclusion criteria
* Under 18 years old, 75 years old or older * A person who has inserted a metal object in a skull * A person with complete occlusion of the carotid artery * A person with epilepsy * Pregnant and lactating women * Who is not eligible for the test
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes in cortical activation | Change from baseline (before stimulation) after stimulation during 30 min | changes in cortical activation is measured by functional Near-Infrared-Spectroscopy (fNIRS) (NIRScout, NIRx, Germany) during treadmill gait. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| 10 meter walk test (10MWT) | Before stimulation (baseline); After strimulation during 30 min | Measure of self selected speeds by measuring the time it takes an individual to walk 10 meters. To perform the test, patient walks 10 meters (33 ft) and the time is measured when the leading foot crosses the start line and the finish line. The instructions are: Please walk this distance at your normal pace when I say go. |
| Timed Up and Go test (TUG) | Before stimulation (baseline); After strimulation during 30 min | The Timed Up and Go test (TUG) is a simple test used to assess a person's mobility and requires both static and dynamic balance. It uses the time that a person takes to rise from a chair, walk three meters, turn around, walk back to the chair, and sit down. |
| Gait analysis using surface electromyograph | Before stimulation (baseline); After strimulation during 30 min | Gait analysis is a process of measuring and evaluating the walking patterns of patients by using surface electromyograph. |
| Gait analysis using motion analysis system | Before stimulation (baseline); After strimulation during 30 min | Gait analysis is a process of measuring and evaluating the walking patterns of patients by using motion analysis system. |
Countries
South Korea
Outcome results
None listed