Acute Coronary Syndrome
Conditions
Keywords
netrin-1, acs, reperfuzion
Brief summary
In our study, Netrin -1; We found that patients with ACS increased at the time of admission, decreased TIMI 3 flow after angiography, and higher risk groups in high risk groups such as TIMI and GRACE were found to have higher Netrin-1 levels.
Interventions
OTHERnetrin-1 value on admission to hospital
Sponsors
Aksaray University Training and Research Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
SINGLE (Subject)
Masking description
Patient group; Those diagnosed with ACS over 18 years of age, planned angiography and accepted angiography. The control group consisted of volunteers without disease.
Intervention model description
PATIENT AND CONTROL GROUP will be divided into two.
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Patients over the age of 18 * diagnose ACS * patients undergoing angiography
Exclusion criteria
* CVE history * Neurological disease * Pregnancy and Lactation * Liver failure * Diagnosed malignity * Use of anticonvulsant and nephrotoxic medication * Chronic kidney disease * Not having angiography * Developing acute renal failure after angiography * Patients who rejected to participate were excluded.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| serum netrin-1 value | 30 minute | Netrin-1 in plasma was measured by enzyme-linked immunosorbent assay (ELISA) (Mybıosource MBS044526 ) All assays were performed in duplicate. Plasma Netrin-1 is expressed in picograms (pg) per mg. |
Outcome results
None listed