Myositis, Systemic Lupus Erythematosus, Vasculitis
Conditions
Keywords
Intensive Care Unit, Mortality, Autoimmune Diseases
Brief summary
Autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis, myositis, or anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis, may affect multiple organ systems. Occasionally, patients deteriorate acutely requiring advanced care in an intensive care unit (ICU). In an ICU setting, mortality is estimated with scoring systems, such as APACHE or SAPSII. Since there are limited data available on their use in autoimmune diseases, with the current study, we aim to assess the usefulness of these ICU scores and analyze predictors of mortality in this particular group of patients.
Interventions
OTHERICU Care
No intervention
Sponsors
University Medical Center Goettingen
University of Göttingen
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients admitted to the ICU at the University Medical Center Göttingen
Exclusion criteria
* Patients with incomplete or missing data
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In-hospital mortality | From date of admission to the ICU until the date of death from any cause assessed up to 52 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Need for ventilation | From date of admission to the ICU until the date of event assessed up to 52 weeks |
| Need for catecholamines | From date of admission to the ICU until the date of event assessed up to 52 weeks |
| Risk of renal replacement therapy | From date of admission to the ICU until the date of event assessed up to 52 weeks |
| Need for cardiopulmonary resuscitation | From date of admission to the ICU until the date of event assessed up to 52 weeks |
Countries
Germany
Contacts
Primary ContactPeter Korsten, MD
Backup ContactRadovan Vasko, MD
Outcome results
None listed