Apical Periodontitis, Necrotic Pulp
Conditions
Keywords
Necrotic pulp,, Apical periodontitis, Regeneration, MTA, Biodentine
Brief summary
The aim of this prospective, randomized, controlled double-blind study is to evaluate the effectiveness of biodentine compared with MTA used as pulp space barrier on discoloration of teeth after regenerative based non-obturation root canal treatment in mature single canal with pulp necrosis and apical periodontitis.
Detailed description
• Regenerative endodontic treatment will be performed through two visits: First visit aims to clean and disinfect the tooth canal by copious irrigation with NaOCL and EDTA solution . At the end of first visit, canal will be dressed by CaOH as intracanal medicaments. Second visit will be after two weeks. After removal of CaOH dressing by copius irrigation, evoking bleeding inside canal by over instrumentation. When blood become semi-coagulated, according to the random sequence number of the participants, either biodentine or white MTA will be placed as pulp space barrier. At the end of treatment, the access cavity will be sealed with composite restoration.
Interventions
OTHERBiodentine
Biodentine is calcium silicate based cement which is bioactive and inductive material. Biodentine will be applied as coronal plug material.
OTHERWhite MTA
MTA is calcium silicate based cement which is bioactive and inductive material. MTA is used in most cases of regenerative endodontics and it will be applied as coronal plug material.
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Masking description
Participants/ outcome assessor will be blinded
Eligibility
Sex/Gender
ALL
Age
10 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
1. Tooth type: single-rooted teeth (anterior or premolar) encasing of one root canal with mature root (closed apex). 2. Negative response of pulp tissue to electrical or thermal pulp tester. 3. Widening in lamina dura or periapical radiolucency not more than 3 mm.
Exclusion criteria
* 1\. Patients having significant systemic disorder or immunocompromised patients. 2. Teeth with generalized chronic periodontitis or have periodontal pocket larger than 3 mm. 3\. Teeth with developmental anomalies (i.e, dens invaginatusor a palatogingival groove). 4\. Teeth with previous root canal. 5. Teeth need to post and core as final restoration
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Discoloration of teeth | Up to one Year after completion of regenerative endodontic treatment | Discoloration of teeth that will be assessed clinically through follow up period 3, 6, 9, 12 months by visual examination and by using color shade guide (Tetric N shade guide, Ivoclar Vivadent) whether tooth discolored or not in comparison with the original preoperative color shade. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Healing of Periapical Tissue | after 3, 6,9 and Up to 12 months after completion of regenerative endodontic treatment | Healing of periapical tissue will be assessed clinically and radiographically through follow up period: 3, 6, 9, 12 months. When the case is clinically asymptomatic: (without sinus tract, swelling, with no palpation, or percussions pain) and radiographically showed absence or reduction of the radiolucency are together will considered successful of regenerative treatment. |
| Restoring the sensibility of tooth | after 6,9 and Up to 12 months after completion of regenerative endodontic treatment | Electric pulp tester (EPT) |
Countries
Egypt
Outcome results
None listed