Peripheral Vascular Diseases
Conditions
Brief summary
Non-interventional study aiming to ascertain the mechanical properties of human saphenous and popliteal vein tissue.
Detailed description
The aim of this study is to mechanically characterise saphenous and popliteal vein segments that have been deemed waste following varicose vein procedures, lower limb amputation and lower limb bypass surgery. By characterising the stress-stretch relationship of the vein vessel wall, treatment techniques can be better understood. Mechanical device design can be bteer informed and the the suitability of vein as a conduit for bypass and AVF procedures can be assessed.
Interventions
None listed
Sponsors
University of Limerick
University Hospital of Limerick
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Male or Female patients aged 18 years or older * Patients undergoing varicose vein procedures or; * Patients undergoing lower limb amputation or; * Patients undergoing lower limb bypass surgery
Exclusion criteria
* Patients unable to give informed consent * Seriously ill/unconscious patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The identification of vein tissue mechanical distension and stretching properties. | 2 years | Vein tissue will undergo inflation-extension testing and unilaxial testing. The vein tissue will be cross-sectioned and rings of venous tissue will be mechanically characterised according to the properties exhibited. |
Countries
Ireland
Contacts
Primary ContactFiona Leahy, CNM Research
Outcome results
None listed