Critical Illness, Enteral Feeding Intolerance
Conditions
Keywords
Enteral feeding, vasopressor, lactate
Brief summary
The aim of this study was to evaluate the effect of calorie and enteral feeding timing on survival in critically ill children receiving inotropic, vasopressor and inodilatory supplements.
Detailed description
The aim of this study was to evaluate the effect of calorie and enteral feeding timing on survival in critically ill children receiving inotropic, vasopressor and inodilatory supplements. Early enteral nutrition will be initiated within the first 24 hours of hospitalization in critically ill children who have inotropic vasopressor and inodilator support without any problems and contraindications in gastrointestinal system functions. The energy requirement of the intubated patients will be measured by indirect calorie meter method. Schofield method will be used to calculate the daily energy needs of extubated patients. 30% of the targeted energy in the first 48 hours of hospitalization and 80% of the targeted energy in the first week will be achieved by enteral nutrition.Nutritional solutions with a concentrated formula of 1 / 1.5 will be given to patients with cardiac pulmonary or renal disease requiring fluid restriction.Patients will be followed up for vomiting, diarrhea, abdominal distention, feeding intolerance, gastric residues and gastrointestinal bleeding. If these findings develop, the patient's nutrition will be interrupted according to the clinician's assessment and enteral nutrition will be re-fed as soon as possible.
Interventions
None listed
Sponsors
Cukurova University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
1 Months to 18 Years
Healthy volunteers
No
Inclusion criteria
* Children with normal gastrointestinal system function * Children receiving inotropic, vasopressor or inodilatory support
Exclusion criteria
* Children with gastrointestinal system dysfunction * Children with enteral nutrition contraindicated * Children with metabolic disease with special nutrition
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 28-d mortality | 28 days | To evaluate the effect of enteral feeding timing on survival |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Lactate | During inotropic treatment | To observe safe lactate levels suitable for enteral nutrition. Lactate levels will be measure 4 times in a day. |
| Vasoactive inotrope score | During inotropic treatment | To observe maximum vasoactive inotrope score suitable for enteral nutrition. Maximum VIS will be recorded. |
Countries
Turkey (Türkiye)
Contacts
Primary ContactAhmet Yöntem
Outcome results
None listed