Histopathological Examination of Iris Tissue in Buphthalmos

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04011878

Enrollment

Registered

2019-07-09

Start date

2016-01-31

Completion date

2018-10-31

Last updated

2019-07-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Iris Disease

Brief summary

To revise the etiology of the primary congenital glaucoma in some infants.

Detailed description

Combined trabeculotomy trabeculectomy with mitomycin C was done in 11 eyes. Histopathological examination of the peripheral iris tissue specimen was done in all cases.

Interventions

PROCEDURECombined trabeculotomy trabeculectomy with mitomycin C

Combined trabeculotomy trabeculectomy with mitomycin C with histopathological examination of the peripheral iris tissue specimen of all cases

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* infants under age of 2 years * 1ery glaucoma

Exclusion criteria

* infants more than 2 years * 2ery glaucoma * previous glaucoma surgery

Design outcomes

Primary

Measure	Time frame	Description
fibrovascular membrane over iris surface	6 month	angle closure by a fibrovascular tissue proliferation over the trabecular meshwork in the anterior chamber angle.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026