Schizophrenia
Conditions
Brief summary
Patients with schizophrenia , who visit frenquently day-care or day-care activities clinics, often experience difficulties of daily living and cognitive deficits. Living independently is a key for recovery. Cognitive remediation is a therapy which reduces deficit and improves daily living. Nowadays no program exists targeting neurocognitive functions in virtual reality which could mimic everyday life in a virtual town. Hypotheses : * Persons with schizophrenia experience difficulties in daily living and disabilities to plan in everyday life. PLANI-REV program, a serious game with a navigation in a virtual town, in a 15 weekly group sessions could reduce these difficulties compared to the initial assessment. This improvement could be maintained 6 months after the end of the program. * PLANI-REV could also improve prospective memory, attention, working memory, and visuospatial organization. * PLANI-REV could induce a clinical improvement, as well as better perception of self-efficiency, self esteem, quality of life, and conversation skills.
Interventions
OTHERPLANI-REV
Cognitive remediation program.
OTHERRELAXATION
Stimulation with no cognitive remediation.
Sponsors
Centre Hospitalier St Anne
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* Age between 18 and 50 years old. * Diagnostic of schizophrenia or schizoaffective disorder (DSM V), attested by the MINI structured interview (Shehan et al. 1998) * Who visit for months or year, weekly or several times per week, a day care, or therapeutic activity units outpatients clinics and nursing homes * French Mother tongue * Consent of the legal representative caregiver for the patients under representative law (tutelle in French). * Clinical Stability - Therapeutic stability for at least one month. * National healthcare assurance
Exclusion criteria
* Central Neurological or non stabilized somatic diseases. * Treatments for somatic disease with putative psychotropic effect. * Electroconvulsive therapy in the last six months * Illetrism * IQ\< 70 established with the f-NART. * Substance misuse or dependence (except Nicotine) or toxic for more than 5 years.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Efficacy of PLANI-REV : questionnaire scores | 10 months | the comparison pre/post PLANI-REV of the number of difficulties of daily life using the Profinteg questionnaire |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| - Profinteg scores 6 months after PLANI-REV. Number of problematic activities; average score for difficulties of problematic activities. | 16 months | To improve pre/post PLANI-REV and 6 months after, neuropsychological performances in prospective memory, attention, working memory, executive functions, and visual and spatial organization |
Countries
France
Contacts
Primary ContactIsabelle AMADO, MD
Backup ContactSylvie DOROCANT
Outcome results
None listed