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Mindreading in Adults With Autism Spectrum Disorder

Mindreading in Adults With Autism Spectrum Disorder

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04010409
Enrollment
60
Registered
2019-07-08
Start date
2019-01-08
Completion date
2024-12-31
Last updated
2023-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autism Spectrum Disorder

Brief summary

This study aims to investigate the ability of reading emotions by the Eyes task in adults with ASD, and examine the gazing pattern and frontal activation during the task. We plan to recruit 50 adults with ASD and 50 typically-developing adults. Eye-tracking and frontal activation (measured by functional near-infrared spectroscopy) will be examined during the Eyes task.

Detailed description

Autism spectrum disorder (ASD) is a clinical syndrome characterized by mindreading deficits, or Theory of Mind deficits. The Reading the Mind in the Eyes task (abbreviated as the Eyes task) was developed to assess the mindreading deficits as a hallmark of social deficits of ASD. This study aims to investigate the ability of reading emotions by the Eyes task in adults with ASD, and examine the gazing pattern and frontal activation during the task. We plan to recruit 50 adults with ASD and 50 typically-developing adults. All the participants will complete clinical measures and the Eyes task. Eye-tracking and frontal activation (measured by functional near-infrared spectroscopy) will be examined during the Eyes task.

Interventions

OTHERno intervention

no intervention

Sponsors

National Taiwan University Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
20 Years to 50 Years
Healthy volunteers
Yes

Inclusion criteria

* Adult aged between 20 and 50 years who had a diagnosis of ASD based on DSM-5. * Had a full-scale IQ \> 70 on WAIS-IV.

Exclusion criteria

* A history of major mental illness (e.g., bipolar affective disorder, schizophrenia) or neurological diseases. * Visual impairment and that would preclude participation.

Design outcomes

Primary

MeasureTime frameDescription
eye tracking indicators30 mineye tracking indicators

Countries

Taiwan

Contacts

Primary ContactYi Ling Chien, M.D., Ph.D.
ylchien@hotmail.com886-2-2312-3456

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 8, 2026