ATtention Test and Executive Functions After STroke to Predict Depression.

Predictivity of Attention Test and Executive Functions After Stroke to Predict Depression 3 Months After Stroke.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04008719

Acronym

ATTEST-Depress

Enrollment

Registered

2019-07-05

Start date

2017-05-16

Completion date

2019-09-30

Last updated

2021-05-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke Depression

Keywords

Depression

Brief summary

The purpose of this study is to determine whether cognitive function evaluation (sustained attention, executive functions, working memory) during acute post-stroke is predictive of a 3 months post-stroke depression.

Detailed description

1. Baseline visit: after neurologic stability, 14 days or less after stroke and before discharge. 2. First assessment : 1. Neurologic data: morphologic data (MRI of the brain), stroke severity (NIHSScore), aphasia assessment (Boston Diagnostic Aphasia Examination) if NIHS verbal score ≥1, hemineglect assessment (Bells test). 2. Personal data assessment : i. Socio demographic : age, gender, marital status, employment, level of education ii. Medical history: medical treatments, psychiatric and non psychiatric history. c. Psychiatric assessment i. Mini International Neuropsychiatric Interview - depression ii. Beck Depression Inventory iii. Clinical Global Impression iv. Standardized Assessment of Personality - Abbreviated Scale (SAPAS) v. Fageström-C vi. Alcohol Use Disorders Identification Test (AUDIT-C) d. Cognitive assessment: i. Verbal memory : Dubois's five words ii. Clock drawing test iii. D2test (computerized) iv. Verbal fluency (Cardebat) v. Working memory (digit span WAIS 3) vi. Brixton (computerized) 3. Assessment 3 months after the first assessment. Phone call and psychiatric assessment: MINI depression, Beck Depression Inventory. Barthel index and Quality of Life assessment.

Interventions

OTHERThymic history

This interview concerns mainly the nature of the previous psychiatric and psychological care

OTHEREvaluation of the psychiatric disorders

Mini International Neuropsychiatric Interview for the positive diagnosis of depression - under the MINI score of depression.

OTHERCognitive evaluation

They will be held consecutively to the patient's bedside interview on the same day. Some tests will be computerized, others will be in paper form.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

SCREENING

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age 18 or more * Ischemic or hemorragic stroke, diagnosed with radiology : cerebral CT or MRI, 14 days or less after stroke * Signed Consent * Social insurance regime affiliation

Exclusion criteria

* Death * No possibility of follow-up * No French-speaker : insufficient command of French * Deprivation of liberty : judicial or administrative decision * D2 test assessment impossibility * Aphasia with major disorder of the understanding (Boston \<8) * Antidepressant treatment during stroke * Depression during stroke * protected people

Design outcomes

Primary

Measure	Time frame	Description
Post stroke depression	3 months	Whether or not a post-stroke depression occurs. occurrence of post-stroke depression assessed with Mini International Neuropsychiatric Interview (MINI), subscale depression .

Secondary

Measure	Time frame	Description
Post-stroke depression population characterization	1 day	Age, gender, marital status, occupation, level of education, laterality of stroke,and medical and psychiatric history will be collected during the inclusion interview and cognitive tests

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026