Cardiac Output
Conditions
Keywords
Cardiac Output, vascular medicine, Transcutaneous Oxymetry
Brief summary
Cardiac output (CO) is an essential physiological parameter of healthy person or illness. In clinical practices, all methods of measuring the CO(Fick method, thoracic impedance, esophageal echodoppler etc) contain limit. Each method are dangerous or hard to implement. CO is probably determining element of blood transit time and thus the availability of oxygen between the central organs (heart, lung) and the peripheral organs (leg, arms). Our hypothesis is transcutaneous oxymetry mesurement with oxygen inhalation, to cause a transient hyperoxia, can be used to determinate blood transit time between central organs and peripheral organs. This simple method will be non invasive technique.
Detailed description
At admission eligible patients are proposed to participate. Written consent is signed after complete oral and written explanation of the protocol is signed. The time of onset hyperoxia will be compare to usual CO method by cross correlation. The duration of participation for subject is equal to 1 hour.
Interventions
DIAGNOSTIC_TESTTranscutaneous oxymetry measurement
Transcutaneous oxymetry measurement with transient hyperoxia period (2 periods of 30seconds at 60% of oxygen)
Sponsors
University Hospital, Angers
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Adults over 18 * Cardiac output measurement considered at least 2 hours prior to the study * Affiliation to a French National healthcare system * Written informed consent must be obtained prior to protocol-specific
Exclusion criteria
* Acute or decompensated cardiac or respiratory failure * Allergy to medical adhesives * Patients under reinforced protection, pregnancy, deprived of liberty by judicial or administrative decision, hospitalized without consent or admitted to a health or social establishment for purposes other than research * Inability to understand the instructions or objectives of the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Estimation of transcutaneous oxymetry with transient hyperoxia | 24 months | Transition time calcutation from oxygen to peripheral organs by transcutaneous oxymetry method. |
| Average of CO measured | 24 months | Average of CO by usual method (catheterisation or transoesophageal echocardiography) reported in medical record of patients |
Countries
France
Outcome results
None listed